Recent advances in studies of immune memory in mice and humans have reinforced the
concept that memory B cells play a critical role in protection against repeated infections …

In the past 15 years, B cells have been rediscovered to be not merely bystanders but rather
active participants in autoimmune aetiology. This has been fuelled in part by the clinical …

Adjuvants are critical for improving the quality and magnitude of adaptive immune
responses to vaccination. Lipid nanoparticle (LNP)-encapsulated nucleoside-modified …

In diffuse large B cell lymphoma (DLBCL), tumors belonging to the ABC but not GCB gene
expression subgroup rely upon chronic active B cell receptor signaling for viability, a …

While the antibody response to SARS-CoV-2 has been extensively studied in blood,
relatively little is known about the antibody response in saliva and its relationship to systemic …

B lymphocytes are essential mediators of humoral immunity and play multiple roles in
human cancer. To decode the functions of tumor-infiltrating B cells, we generated a B cell …

Age-associated B cells (ABCs) are formed under inflammatory conditions and are
considered a type of memory B cell (MBC) expressing the transcription factor T-bet. In SLE …

Age-associated B cells (ABCs) are a transcriptionally and functionally unique B cell
population. In addition to arising with age and following infection, ABCs are expanded …

CD11c+ atypical B cells (ABCs) are an alternative memory B cell lineage associated with
immunization, infection, and autoimmunity. However, the factors that drive the transcriptional …

Immunological memory is a composite of lasting antibody titers maintained by plasma cells
in conjunction with memory T and B cells. Memory B cells are a critical reservoir for plasma …