Formation of UV-induced DNA damage contributing to skin cancer development

J Cadet, T Douki - Photochemical & Photobiological Sciences, 2018 - pubs.rsc.org
UV-induced DNA damage plays a key role in the initiation phase of skin cancer. When left
unrepaired or when damaged cells are not eliminated by apoptosis, DNA lesions express …

Formation and repair of oxidatively generated damage in cellular DNA

J Cadet, KJA Davies, MHG Medeiros… - Free Radical Biology …, 2017 - Elsevier
In this review article, emphasis is placed on the critical survey of available data concerning
modified nucleobase and 2-deoxyribose products that have been identified in cellular DNA …

Guanine radicals induced in DNA by low-energy photoionization

E Balanikas, A Banyasz, T Douki… - Accounts of Chemical …, 2020 - ACS Publications
Conspectus Guanine (G) radicals are precursors to DNA oxidative damage, correlated with
carcinogenesis and aging. During the past few years, we demonstrated clearly an intriguing …

Adenine radical cation formation by a ligand-centered excited state of an intercalated chromium polypyridyl complex leads to enhanced DNA photo-oxidation

FA Baptista, D Krizsan, M Stitch… - Journal of the …, 2021 - ACS Publications
Assessment of the DNA photo-oxidation and synthetic photocatalytic activity of chromium
polypyridyl complexes is dominated by consideration of their long-lived metal-centered …

Absorption of low-energy UV radiation by human telomere G-quadruplexes generates long-lived guanine radical cations

A Banyasz, L Martinez-Fernandez, C Balty… - Journal of the …, 2017 - ACS Publications
Telomeres, which are involved in cell division, carcinogenesis, and aging and constitute
important therapeutic targets, are prone to oxidative damage. This propensity has been …

Plasmon-Mediated Photoelectrochemical Hot-Hole Oxidation Coupling Reactions of Adenine on Nanostructured Silver Electrodes

YQ Su, J Liu, R Huang, HT Yang, MX Li… - The Journal of …, 2023 - ACS Publications
Surface-enhanced Raman spectroscopy (SERS) has been widely applied in the
identification and characterization of DNA structures with high efficiency. Especially, the …

Contribution of oxidation reactions to photo‐induced damage to cellular DNA

J Cadet, D Angelov, P Di Mascio… - Photochemistry and …, 2024 - Wiley Online Library
This review article is aimed at providing updated information on the contribution of
immediate and delayed oxidative reactions to the photo‐induced damage to cellular …

Studying the excited electronic states of guanine rich DNA quadruples by quantum mechanical methods: main achievements and perspectives

L Martínez-Fernández, L Esposito, R Improta - … & Photobiological Sciences, 2020 - Springer
The main insights into the photoactivated dynamics of guanine quadruplexes (G4s) recently
provided by quantum mechanical computations are concisely reviewed here. The …

Adenine radicals generated in alternating AT duplexes by direct absorption of low-energy UV radiation

A Banyasz, T Ketola, L Martínez-Fernández… - Faraday …, 2018 - pubs.rsc.org
There is increasing evidence that the direct absorption of photons with energies that are
lower than the ionization potential of nucleobases may result in oxidative damage to DNA …

Exciton trap** dynamics in DNA multimers

R Borrego-Varillas, G Cerullo… - The Journal of Physical …, 2019 - ACS Publications
Using as a model the single adenine strand (dA) 20, we study the ultrafast evolution of
electronic excitations in DNA with a time resolution of 30 fs. Our transient absorption spectra …