[HTML][HTML] Dysregulated signalling pathways driving anticancer drug resistance

N Bou Antoun, AM Chioni - International journal of molecular sciences, 2023‏ - mdpi.com
One of the leading causes of death worldwide, in both men and women, is cancer. Despite
the significant development in therapeutic strategies, the inevitable emergence of drug …

[HTML][HTML] Metformin improves ovarian cancer sensitivity to paclitaxel and platinum-based drugs: a review of in vitro findings

G Tossetta - International Journal of Molecular Sciences, 2022‏ - mdpi.com
Ovarian cancer is one of the most dangerous gynecologic cancers worldwide, showing a
high fatality rate and recurrence due to diagnosis at an advanced stage of the disease and …

[HTML][HTML] Apoptotic induction and anti-metastatic activity of eugenol encapsulated chitosan nanopolymer on rat glioma C6 cells via alleviating the MMP signaling …

Z Li, VP Veeraraghavan, SK Mohan, SR Bolla… - … of Photochemistry and …, 2020‏ - Elsevier
Glioma is the prime cause of cancer allied mortality in adolescent people and it accounts
about 80% of all malignant tumours. Eugenol is a major bioactive constituent present in the …

[HTML][HTML] NF-κB signaling in ovarian cancer

BS Harrington, CM Annunziata - Cancers, 2019‏ - mdpi.com
The NF-κB signaling pathway is a master and commander in ovarian cancer (OC) that
promotes chemoresistance, cancer stem cell maintenance, metastasis and immune evasion …

The hallmarks of ovarian cancer stem cells and niches: Exploring their harmonious interplay in therapy resistance

T Motohara, GJ Yoshida, H Katabuchi - Seminars in Cancer Biology, 2021‏ - Elsevier
The concept of a “cancer stem cell” has evolved over the past decades, and research on
cancer stem cell biology has entered into a stage of remarkable progress. Cancer stem cells …

Mesoporous bioactive glasses (MBGs) in cancer therapy: Full of hope and promise

S Kargozar, M Mozafari, S Hamzehlou, HW Kim… - Materials Letters, 2019‏ - Elsevier
Implementing novel approaches for cancer therapy are under continuous progress, and
bioactive glasses (BGs) and glass-ceramics show excellent potential in this regard. Although …

The capacity of the ovarian cancer tumor microenvironment to integrate inflammation signaling conveys a shorter disease-free interval

KR Jordan, MJ Sikora, JE Slansky, A Minic… - Clinical Cancer …, 2020‏ - aacrjournals.org
Purpose: Ovarian cancer has one of the highest deaths to incidence ratios across all
cancers. Initial chemotherapy is effective, but most patients develop chemoresistant disease …

Small molecule inhibitor of TLR4 inhibits ovarian cancer cell proliferation: new insight into the anticancer effect of TAK-242 (Resatorvid)

B Kashani, Z Zandi, D Bashash, A Zaghal… - Cancer Chemotherapy …, 2020‏ - Springer
Background Despite all advances in the treatment of ovarian cancer (OC), it remains the
most lethal gynecological malignancy worldwide. There are growing amounts of evidence …

DNA damage response and repair in ovarian cancer: Potential targets for therapeutic strategies

M Mirza-Aghazadeh-Attari, C Ostadian, AA Saei… - DNA repair, 2019‏ - Elsevier
Ovarian cancer is among the most lethal gynecologic malignancies with a poor survival
prognosis. The current therapeutic strategies involve surgery and chemotherapy. Research …

Caffeic acid phenethyl ester suppressed growth and metastasis of nasopharyngeal carcinoma cells by inactivating the NF-κB pathway

Y Liang, G Feng, L Wu, S Zhong, X Gao… - Drug design …, 2019‏ - Taylor & Francis
Purpose: Caffeic acid phenethyl ester (CAPE) is the main polyphenol extracted from
honeybee propolis, which inhibits the growth of several kinds of tumor. This study aimed to …