Comprehensive review of targeted therapy for colorectal cancer
YH **e, YX Chen, JY Fang - Signal transduction and targeted therapy, 2020 - nature.com
Colorectal cancer (CRC) is among the most lethal and prevalent malignancies in the world
and was responsible for nearly 881,000 cancer-related deaths in 2018. Surgery and …
and was responsible for nearly 881,000 cancer-related deaths in 2018. Surgery and …
Preoperative chemotherapy for operable colon cancer: mature results of an international randomized controlled trial
PURPOSE Neoadjuvant chemotherapy (NAC) has potential advantages over standard
postoperative chemotherapy for locally advanced colon cancer but requires formal …
postoperative chemotherapy for locally advanced colon cancer but requires formal …
ctDNA and adjuvant therapy for colorectal cancer: time to re-invent our treatment paradigm
M Naidoo, P Gibbs, J Tie - Cancers, 2021 - mdpi.com
Simple Summary There is currently a lack of useful tests to detect microscopic residual
disease in patients who have undergone surgery to remove their bowel cancer. This inability …
disease in patients who have undergone surgery to remove their bowel cancer. This inability …
[HTML][HTML] Localised colon cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
Colorectal cancer (CRC) is the third most common tumour in men and the second in women,
accounting for 10% of all tumour types worldwide. Incidence is 25% higher in males and …
accounting for 10% of all tumour types worldwide. Incidence is 25% higher in males and …
The American Society of Colon and Rectal Surgeons clinical practice guidelines for the management of colon cancer
METHODS This guideline is based on the previous colon cancer parameter published in
2017. 10 Compared with 2017, this guideline has 11 new, 10 updated, and 2 excluded …
2017. 10 Compared with 2017, this guideline has 11 new, 10 updated, and 2 excluded …
Adoption of total neoadjuvant therapy for locally advanced rectal cancer
Importance Treatment of locally advanced rectal (LARC) cancer involves chemoradiation,
surgery, and chemotherapy. The concept of total neoadjuvant therapy (TNT), in which …
surgery, and chemotherapy. The concept of total neoadjuvant therapy (TNT), in which …
A clinical decision support system optimising adjuvant chemotherapy for colorectal cancers by integrating deep learning and pathological staging markers: a …
A Kleppe, OJ Skrede, S De Raedt, TS Hveem… - The lancet …, 2022 - thelancet.com
Summary Background The DoMore-v1-CRC marker was recently developed using deep
learning and conventional haematoxylin and eosin-stained tissue sections, and was …
learning and conventional haematoxylin and eosin-stained tissue sections, and was …
Pre-and postoperative capecitabine without or with oxaliplatin in locally advanced rectal cancer: PETACC 6 trial by EORTC GITCG and ROG, AIO, AGITG, BGDO, and …
HJ Schmoll, A Stein, E Van Cutsem, T Price… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE The PETACC 6 trial investigates whether the addition of oxaliplatin to
preoperative capecitabine-based chemoradiation and postoperative capecitabine improves …
preoperative capecitabine-based chemoradiation and postoperative capecitabine improves …
Three versus 6 months of oxaliplatin-based adjuvant chemotherapy for patients with stage III colon cancer: disease-free survival results from a randomized, open-label …
Purpose Reduction of adjuvant treatment duration may decrease toxicities without loss of
efficacy in stage III colon cancer. This could offer clear advantages to patients and health …
efficacy in stage III colon cancer. This could offer clear advantages to patients and health …
Adjuvant capecitabine plus bevacizumab versus capecitabine alone in patients with colorectal cancer (QUASAR 2): an open-label, randomised phase 3 trial
Background Antiangiogenic agents have established efficacy in the treatment of metastatic
colorectal cancer. We investigated whether bevacizumab could improve disease-free …
colorectal cancer. We investigated whether bevacizumab could improve disease-free …