[HTML][HTML] The'middle-aging'brain

S Dohm-Hansen, JA English, A Lavelle… - Trends in …, 2024 - cell.com
Middle age has historically been an understudied period of life compared to older age, when
cognitive and brain health decline are most pronounced, but the scope for intervention may …

Relating sex-bias in human cortical and hippocampal microstructure to sex hormones

S Küchenhoff, Ş Bayrak, RG Zsido, A Saberi… - Nature …, 2024 - nature.com
Determining sex-bias in brain structure is of great societal interest to improve diagnostics
and treatment of brain-related disorders. So far, studies on sex-bias in brain structure …

Estrogens and human brain networks: A systematic review of structural and functional neuroimaging studies

R Livia, H Kim, M Emily, MM Luise, S Haiko… - Frontiers in …, 2024 - Elsevier
Estrogen fluctuations during the menstrual cycle, puberty, postpartum, or in the menopausal
transition are associated with cognitive, affective, and behavioral effects. Additionally …

Menstrual cycle‐driven hormone concentrations co‐fluctuate with white and gray matter architecture changes across the whole brain

EJ Rizor, V Babenko, NM Dundon… - Human Brain …, 2024 - Wiley Online Library
Cyclic fluctuations in hypothalamic–pituitary–gonadal axis (HPG‐axis) hormones exert
powerful behavioral, structural, and functional effects through actions on the mammalian …

Diurnal fluctuations in steroid hormones tied to variation in intrinsic functional connectivity in a densely sampled male

H Grotzinger, L Pritschet, P Shapturenka… - Journal of …, 2024 - Soc Neuroscience
Most of mammalian physiology is under the control of biological rhythms, including the
endocrine system with time-varying hormone secretion. Precision neuroimaging studies …

Associations of endogenous estrogens, plasma Alzheimer's disease biomarkers, and APOE4 carrier status on regional brain volumes in postmenopausal women

KA Wugalter, RA Schroeder, RC Thurston… - Frontiers in Aging …, 2024 - frontiersin.org
Background Women carrying the APOE4 allele are at greater risk of develo** Alzheimer's
disease (AD) from ages 65–75 years compared to men. To better understand the elevated …

Hippocampal volume and affect in response to fluctuating estrogens in menstrual cycle irregularity: a longitudinal single-subject study

C Heller, D Güllmar, CJ Koeppel, P Rojczyk… - npj Women's …, 2024 - nature.com
Irregular menstrual cycles, affecting approximately 30% of women in their reproductive
years, are often overlooked in research, limiting our insights into the broader spectrum of …

Temporal dissociation between local and global functional adaptations of the maternal brain to childbirth: a longitudinal assessment

LD Lotter, S Nehls, E Losse, J Dukart… - …, 2024 - nature.com
The maternal brain undergoes significant reorganization during birth and the postpartum
period. However, the temporal dynamics of these changes remain unclear. Using resting …

[HTML][HTML] Menopause status-and sex-related differences in age associations with spatial context memory and white matter microstructure at midlife

R Lissaman, S Rajagopal, J Kearley, S Pasvanis… - Neurobiology of …, 2024 - Elsevier
Decline in spatial context memory emerges in midlife, the time when most females transition
from pre-to post-menopause. Recent evidence suggests that, among post-menopausal …

Spotlighting SHAPERS: sex hormones associated with psychological and endocrine roles

N Petersen - Neuropsychopharmacology, 2024 - nature.com
Imagine that your laboratory discovers a signaling molecule in the brain. This molecule can
increase and decrease cortical and subcortical volumes and change brain-wide functional …