[HTML][HTML] Application of quality by design in the current drug development

L Zhang, S Mao - Asian journal of pharmaceutical sciences, 2017 - Elsevier
Quality by Test was the only way to guarantee quality of drug products before FDA launched
current Good Manufacturing Practice. To clearly understand the manufacture processes …

[HTML][HTML] Raman spectroscopy in pharmaceutical product design

A Paudel, D Raijada, J Rantanen - Advanced drug delivery reviews, 2015 - Elsevier
Almost 100 years after the discovery of the Raman scattering phenomenon, related
analytical techniques have emerged as important tools in biomedical sciences. Raman …

Pharmaceutical cocrystals, salts and polymorphs: Advanced characterization techniques

E Pindelska, A Sokal, W Kolodziejski - Advanced drug delivery reviews, 2017 - Elsevier
The main goal of a novel drug development is to obtain it with optimal physiochemical,
pharmaceutical and biological properties. Pharmaceutical companies and scientists modify …

Current trends on medical and pharmaceutical applications of inkjet printing technology

N Scoutaris, S Ross, D Douroumis - Pharmaceutical research, 2016 - Springer
Inkjet printing is an attractive material deposition and patterning technology that has
received significant attention in the recent years. It has been exploited for novel applications …

Novel aspects of Raman spectroscopy in skin research

D Lunter, V Klang, D Kocsis… - Experimental …, 2022 - Wiley Online Library
The analytical technology of Raman spectroscopy has an almost 100‐year history. During
this period, many modifications and developments happened in the method like discovery of …

Mid-infrared photothermal imaging of active pharmaceutical ingredients at submicrometer spatial resolution

C Li, D Zhang, MN Slipchenko, JX Cheng - Analytical chemistry, 2017 - ACS Publications
Chemical imaging with sufficient spatial resolution to resolve microparticles in tablets is
essential to ensure high quality and efficacy in controlled release. The existing modalities …

[HTML][HTML] Raman map**-based non-destructive dissolution prediction of sustained-release tablets

DL Galata, B Zsiros, LA Mészáros, B Nagy… - … of Pharmaceutical and …, 2022 - Elsevier
In this paper, the applicability of Raman chemical imaging for the non-destructive prediction
of the in vitro dissolution profile of sustained-release tablets is demonstrated for the first time …

Studies of silicon nanoparticles uptake and biodegradation in cancer cells by Raman spectroscopy

E Tolstik, LA Osminkina, C Matthäus… - … , Biology and Medicine, 2016 - Elsevier
In-vitro Raman micro-spectroscopy was used for diagnostics of the processes of uptake and
biodegradation of porous silicon nanoparticles (SiNPs) in breast cancer cells (MCF-7 cell …

Data processing of vibrational chemical imaging for pharmaceutical applications

PY Sacré, C De Bleye, PF Chavez… - … of Pharmaceutical and …, 2014 - Elsevier
Vibrational spectroscopy (MIR, NIR and Raman) based hyperspectral imaging is one of the
most powerful tools to analyze pharmaceutical preparation. Indeed, it combines the …

Raman micro spectroscopy for in vitro drug screening: subcellular localisation and interactions of doxorubicin

Z Farhane, F Bonnier, A Casey, HJ Byrne - Analyst, 2015 - pubs.rsc.org
Vibrational spectroscopy, including Raman micro spectroscopy, has been widely used over
the last few years to explore potential biomedical applications. Indeed, Raman micro …