It was once widely held that nearly all reactions in biology were catalyzed via mechanisms
involving paired electron species. Beginning approximately 40 years ago, this paradigm was …

Deazaguanine modifications play multifaceted roles in the molecular biology of DNA and
tRNA, sha** diverse yet essential biological processes, including the nuanced fine-tuning …

Microbial arsenic (As) methylation and demethylation are important components of the As
biogeochemical cycle. Arsenic methylation is enhanced under flooded conditions in paddy …

Radical S-adenosyl-l-methionine (SAM) enzymes belong to a family of catalysts whose
number of annotated sequences is still growing. Upon the one-electron reduction of a …

S-Adenosylmethionine (SAM, also known as AdoMet) radical enzymes use SAM and a [4Fe-
4S] cluster to catalyze a diverse array of reactions. They adopt a partial triose-phosphate …

Covering: up to the end of 2017 The human body is composed of an equal number of
human and microbial cells. While the microbial community inhabiting the human …

By catalysing the microbial formation of methane, methyl-coenzyme M reductase has a
central role in the global levels of this greenhouse gas,. The activity of methyl-coenzyme M …

Abstract Oxetanocin A (OXT-A) is a potent antitumour, antiviral and antibacterial compound.
Biosynthesis of OXT-A has been linked to a plasmid-borne Bacillus megaterium gene cluster …

The members of the radical S-adenosylmethionine (SAM) enzyme superfamily are
responsible for catalyzing a diverse set of reactions in a multitude of biosynthetic pathways …

Conspectus Metal ions and metallocofactors play important roles in a broad range of
biochemical reactions. Accordingly, it has been estimated that as much as 25–50% of the …