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1, 3, 4-Thiadiazole: synthesis, reactions, and applications in medicinal, agricultural, and materials chemistry
Y Hu, CY Li, XM Wang, YH Yang, HL Zhu - Chemical reviews, 2014 - ACS Publications
Over the past decades, the bulk of chemists' interests have been on heterocyclic compounds
and their various derivatives as well as their applications in the pharmaceutical and …
and their various derivatives as well as their applications in the pharmaceutical and …
Natural and synthetic coumarins as antileishmanial agents: A review
The neglected tropical disease leishmaniasis is still a major public health problem that
affects millions of people worldwide. Related to poor-living conditions, this vector-borne …
affects millions of people worldwide. Related to poor-living conditions, this vector-borne …
Secondary metabolites: Secondary metabolic products consisting of C and H; C, H, and O; N, S, and P elements; and O/N heterocycles
ANM Alamgir, ANM Alamgir - Therapeutic use of medicinal plants and their …, 2018 - Springer
Terpenes and terpenoids, steroids and sterols, volatile oils, miscellaneous isoprenoids,
phenols and phenyl propanoids, alkaloids, glycosides, bitter principles, resins, saponins …
phenols and phenyl propanoids, alkaloids, glycosides, bitter principles, resins, saponins …
Synthesis and anti-leishmanial activity of 5-(5-nitrofuran-2-yl)-1, 3, 4-thiadiazol-2-amines containing N-[(1-benzyl-1H-1, 2, 3-triazol-4-yl) methyl] moieties
A novel series of 5-(5-nitrofuran-2-yl)-1, 3, 4-thiadiazol-2-amines were synthesized by
introducing N-[(1-benzyl-1H-1, 2, 3-triazol-4-yl) methyl] moiety as a new functionality on the …
introducing N-[(1-benzyl-1H-1, 2, 3-triazol-4-yl) methyl] moiety as a new functionality on the …
Trypanosomatidae diseases: from the current therapy to the efficacious role of trypanothione reductase in drug discovery
LSC Bernardes, CL Zani… - Current medicinal …, 2013 - ingentaconnect.com
According to World Health Organization (WHO), trypanosomiasis and leishmaniasis are the
most challenging among the neglected tropical diseases. Comparative studies between …
most challenging among the neglected tropical diseases. Comparative studies between …
Antiprotozoal agents: How have they changed over a decade?
Neglected tropical diseases are a diverse group of communicable diseases that are
endemic in low‐or low‐to‐middle‐income countries located in tropical and subtropical …
endemic in low‐or low‐to‐middle‐income countries located in tropical and subtropical …
Synthesis and antileishmanial evaluation of 1-aryl-4-(4, 5-dihydro-1H-imidazol-2-yl)-1H-pyrazole derivatives
MS dos Santos, MLV Oliveira, AMR Bernardino… - Bioorganic & medicinal …, 2011 - Elsevier
A series of 1-aryl-4-(4, 5-dihydro-1H-imidazol-2-yl)-1H-pyrazoles (4a–g) and 5-amino-1-aryl-
4-(4, 5-dihydro-1H-imidazol-2-yl)-1H-pyrazoles (5a–g) were synthesized and evaluated in …
4-(4, 5-dihydro-1H-imidazol-2-yl)-1H-pyrazoles (5a–g) were synthesized and evaluated in …
Intestinal targeting of drugs: rational design approaches and challenges
Targeting drugs to the gastrointestinal tract has been and continues to be an active area of
research. Guttargeting is an effective means of increasing the local concentration of active …
research. Guttargeting is an effective means of increasing the local concentration of active …
Leishmanicidal, antiproteolytic and antioxidant evaluation of natural biflavonoids isolated from Garcinia brasiliensis and their semisynthetic derivatives
VS Gontijo, WAS Judice, B Codonho, IO Pereira… - European journal of …, 2012 - Elsevier
The natural biflavonoids morelloflavone-4‴-O-β-d-glycosyl (1),(±)-fukugiside (2) and
morelloflavone (3) were isolated from the ethyl acetate extract (EAEE) of dried and …
morelloflavone (3) were isolated from the ethyl acetate extract (EAEE) of dried and …
Synthesis and biological evaluation of some novel 1-indanone thiazolylhydrazone derivatives as anti-Trypanosoma cruzi agents
ME Caputto, A Ciccarelli, F Frank, AG Moglioni… - European journal of …, 2012 - Elsevier
A series of novel 4-arylthiazolylhydrazones (TZHs) derived from 1-indanones were
synthesized in good yields (66–92%) in a simple procedure using microwave irradiation and …
synthesized in good yields (66–92%) in a simple procedure using microwave irradiation and …