iProt-Sub: a comprehensive package for accurately map** and predicting protease-specific substrates and cleavage sites
Regulation of proteolysis plays a critical role in a myriad of important cellular processes. The
key to better understanding the mechanisms that control this process is to identify the …
key to better understanding the mechanisms that control this process is to identify the …
Identify origin of replication in Saccharomyces cerevisiae using two-step feature selection technique
Motivation DNA replication is a key step to maintain the continuity of genetic information
between parental generation and offspring. The initiation site of DNA replication, also called …
between parental generation and offspring. The initiation site of DNA replication, also called …
PROSPER: an integrated feature-based tool for predicting protease substrate cleavage sites
The ability to catalytically cleave protein substrates after synthesis is fundamental for all
forms of life. Accordingly, site-specific proteolysis is one of the most important post …
forms of life. Accordingly, site-specific proteolysis is one of the most important post …
PVP-SVM: sequence-based prediction of phage virion proteins using a support vector machine
Accurately identifying bacteriophage virion proteins from uncharacterized sequences is
important to understand interactions between the phage and its host bacteria in order to …
important to understand interactions between the phage and its host bacteria in order to …
[HTML][HTML] SuSPect: enhanced prediction of single amino acid variant (SAV) phenotype using network features
Whole-genome and exome sequencing studies reveal many genetic variants between
individuals, some of which are linked to disease. Many of these variants lead to single amino …
individuals, some of which are linked to disease. Many of these variants lead to single amino …
Challenges in the diagnosis and discovery of rare genetic disorders using contemporary sequencing technologies
Next generation sequencing (NGS) has revolutionised rare disease diagnostics.
Concomitant with advancing technologies has been a rise in the number of new gene …
Concomitant with advancing technologies has been a rise in the number of new gene …
PREvaIL, an integrative approach for inferring catalytic residues using sequence, structural, and network features in a machine-learning framework
Determining the catalytic residues in an enzyme is critical to our understanding the
relationship between protein sequence, structure, function, and enhancing our ability to …
relationship between protein sequence, structure, function, and enhancing our ability to …
RFhy-m2G: identification of RNA N2-methylguanosine modification sites based on random forest and hybrid features
C Ao, Q Zou, L Yu - Methods, 2022 - Elsevier
N2-methylguanosine is a post-transcriptional modification of RNA that is found in eukaryotes
and archaea. The biological function of m2G modification discovered so far is to control and …
and archaea. The biological function of m2G modification discovered so far is to control and …
DHSpred: support-vector-machine-based human DNase I hypersensitive sites prediction using the optimal features selected by random forest
DNase I hypersensitive sites (DHSs) are genomic regions that provide important information
regarding the presence of transcriptional regulatory elements and the state of chromatin …
regarding the presence of transcriptional regulatory elements and the state of chromatin …
ASPIRER: a new computational approach for identifying non-classical secreted proteins based on deep learning
Protein secretion has a pivotal role in many biological processes and is particularly
important for intercellular communication, from the cytoplasm to the host or external …
important for intercellular communication, from the cytoplasm to the host or external …