OCT Biomarkers in Neovascular Age‐Related Macular Degeneration: A Narrative Review

C Metrangolo, S Donati, M Mazzola… - Journal of …, 2021 - Wiley Online Library
Age‐related macular degeneration (AMD) is the leading cause of legal blindness in elderly
people. Neovascular AMD (nAMD) is responsible for the majority of cases of severe visual …

Fluid as a critical biomarker in neovascular age-related macular degeneration management: literature review and consensus recommendations

L Kodjikian, M Parravano, A Clemens, R Dolz-Marco… - Eye, 2021 - nature.com
Current guidelines on the management of patients with neovascular age-related macular
degeneration (nAMD) lack clear recommendations on the interpretation of fluid as seen on …

[HTML][HTML] Quantitative analysis of OCT for neovascular age-related macular degeneration using deep learning

G Moraes, DJ Fu, M Wilson, H Khalid, SK Wagner… - Ophthalmology, 2021 - Elsevier
Purpose To apply a deep learning algorithm for automated, objective, and comprehensive
quantification of optical coherence tomography (OCT) scans to a large real-world dataset of …

Deep learning-based single-shot prediction of differential effects of anti-VEGF treatment in patients with diabetic macular edema

R Rasti, MJ Allingham, PS Mettu, S Kavusi… - Biomedical optics …, 2020 - opg.optica.org
Anti-vascular endothelial growth factor (VEGF) agents are widely regarded as the first line of
therapy for diabetic macular edema (DME) but are not universally effective. An automatic …

Optical coherence tomography imaging biomarkers associated with neovascular age-related macular degeneration: a systematic review

RLW Hanson, A Airody, S Sivaprasad, RP Gale - Eye, 2023 - nature.com
The aim of this systematic literature review is twofold,(1) detail the impact of retinal
biomarkers identifiable via optical coherence tomography (OCT) on disease progression …

Evaluating an automated machine learning model that predicts visual acuity outcomes in patients with neovascular age-related macular degeneration

A Abbas, C O'Byrne, DJ Fu, G Moraes… - Graefe's Archive for …, 2022 - Springer
Purpose Neovascular age-related macular degeneration (nAMD) is a major global cause of
blindness. Whilst anti-vascular endothelial growth factor (anti-VEGF) treatment is effective …

Predicting incremental and future visual change in neovascular age-related macular degeneration using deep learning

DJ Fu, L Faes, SK Wagner, G Moraes, R Chopra… - Ophthalmology …, 2021 - Elsevier
Purpose To evaluate the predictive usefulness of quantitative imaging biomarkers, acquired
automatically from OCT scans, of cross-sectional and future visual outcomes of patients with …

Association between visual acuity, lesion activity markers and retreatment decisions in neovascular age-related macular degeneration

U Chakravarthy, N Pillai, A Syntosi, L Barclay, C Best… - Eye, 2020 - nature.com
Background/objectives To investigate the association between optical coherence
tomography (OCT) markers of lesion activity and changes in visual acuity (VA) during anti …

AMD-SD: An Optical Coherence Tomography Image Dataset for wet AMD Lesions Segmentation

Y Hu, Y Gao, W Gao, W Luo, Z Yang, F **ong, Z Chen… - Scientific Data, 2024 - nature.com
Abstract Wet Age-related Macular Degeneration (wet AMD) is a common ophthalmic
disease that significantly impacts patients' vision. Optical coherence tomography (OCT) …

[HTML][HTML] Longitudinal assessment of ellipsoid zone integrity, subretinal hyperreflective material, and subretinal pigment epithelium disease in neovascular age-related …

JP Ehlers, R Zahid, PK Kaiser, JS Heier, DM Brown… - Ophthalmology …, 2021 - Elsevier
Purpose To assess longitudinally the effect of anti–vascular endothelial growth factor
(VEGF) treatment on ellipsoid zone (EZ) integrity, subretinal hyperreflective material …