The causative agent of tuberculosis (TB), Mycobacterium tuberculosis and more recently
totally drug‐resistant strains of M. tuberculosis, display unique mechanisms to survive in the …

The discovery of nalidixic acid is one pinnacle in medicinal chemistry, which opened a new
area of research that has led to the discovery of several life-saving antimicrobial agents …

Multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis are generally
thought to have high mortality rates. However, many cases can be treated with the right …

The emergence and wide-spread of drug-resistant bacteria including multi-drug resistant
and pan-drug resistant pathogens which are associated with considerable mortality …

Tuberculosis (TB) remains a global public health problem in recent years. TB originated
mainly from various strains of Mycobacterium tuberculosis, is a highly infectious and chronic …

Pathogenic microorganisms are causative agents for different types of serious and even
lethal infectious diseases. Despite advancements in medication, bacterial and fungal …

Gram-positive bacteria are responsible for a broad range of infectious diseases, and the
emergency and wide spread of drug-resistant Gram-positive pathogens including MRSA …

SETTING: Niger National Tuberculosis Programme. Regions supported by the Damien
Foundation. OBJECTIVE: To evaluate the effectiveness of a short-course standardised …

The molecular mechanisms determining the transmissibility and prevalence of drug-resistant
tuberculosis in a population were investigated through whole-genome sequencing of 1,000 …

Infectious diseases caused by clinically important Mycobacteria continue to be an important
public health problem worldwide primarily due to emergence of drug resistance crisis. In …