Magnetic resonance imaging and computed tomography from multiple batches (eg sites,
scanners, datasets, etc.) are increasingly used alongside complex downstream analyses to …

Proton MRS (1H MRS) provides noninvasive, quantitative metabolite profiles of tissue and
has been shown to aid the clinical management of several brain diseases. Although most …

The spinocerebellar ataxias (SCAs) comprise more than 40 autosomal dominant
neurodegenerative disorders that present principally with progressive ataxia. Within the past …

Conventional proton MRS has been successfully utilized to noninvasively assess tissue
biochemistry in conditions that result in large changes in metabolite levels. For more …

Key points The ability to learn new motor skills is supported by plasticity in the structural and
functional organisation of the primary motor cortex in the human brain. Changes inhibitory to …

Magnetic resonance spectroscopy (MRS) is the only biomedical imaging method that can
noninvasively detect endogenous signals from the neurotransmitter γ-aminobutyric acid …

With a 40‐year history of use for in vivo studies, the terminology used to describe the
methodology and results of magnetic resonance spectroscopy (MRS) has grown …

Purpose To determine the test‐retest reproducibility of neurochemical concentrations
obtained with a highly optimized, short‐echo, single‐voxel proton MR spectroscopy (MRS) …

Brain stimulation approaches are important to gain causal mechanistic insights into the
relevance of functional brain regions and/or neurophysiological systems for human cognitive …

Combined fMRI-MRS is a novel method to non-invasively investigate functional activation in
the human brain using simultaneous acquisition of hemodynamic and neurochemical …