Just breathe: a review of sex and gender in chronic lung disease

R Somayaji, JD Chalmers - European Respiratory Review, 2022 - publications.ersnet.org
Chronic lung diseases are the third leading cause of death worldwide and are increasing in
prevalence over time. Although much of our traditional understanding of health and disease …

Impact of low‐dose computed tomography (LDCT) screening on lung cancer‐related mortality

A Bonney, R Malouf, C Marchal… - Cochrane Database …, 2022 - cochranelibrary.com
Background Lung cancer is the most common cause of cancer‐related death in the world,
however lung cancer screening has not been implemented in most countries at a population …

Gender differences in COPD: are women more susceptible to smoking effects than men?

IC Sørheim, A Johannessen, A Gulsvik, PS Bakke… - Thorax, 2010 - thorax.bmj.com
Background The number of female smokers develo** chronic obstructive pulmonary
disease (COPD) is rapidly increasing, but whether or not there exists a differential …

Combined pulmonary fibrosis and emphysema syndrome: a review

MD Jankowich, SIS Rounds - Chest, 2012 - Elsevier
There is increasing clinical, radiologic, and pathologic recognition of the coexistence of
emphysema and pulmonary fibrosis in the same patient, resulting in a clinical syndrome …

Contribution of adaptive immunity to human COPD and experimental models of emphysema

F Kheradmand, Y Zhang, DB Corry - Physiological Reviews, 2023 - journals.physiology.org
The pathophysiology of chronic obstructive pulmonary disease (COPD) and the undisputed
role of innate immune cells in this condition have dominated the field in the basic research …

COPD and gender differences: an update

S Aryal, E Diaz-Guzman, DM Mannino - Translational Research, 2013 - Elsevier
Chronic obstructive lung disease (COPD) is one of the most prevalent health conditions, and
a major cause of morbidity and mortality around the globe. Once thought of primarily as a …

Sex differences in chronic obstructive pulmonary disease mechanisms

PJ Barnes - American journal of respiratory and critical care …, 2016 - atsjournals.org
In the past, chronic obstructive pulmonary disease (COPD) was always considered to be a
disease that mainly affected elderly men, reflecting the high prevalence of smoking among …

Early-onset chronic obstructive pulmonary disease is associated with female sex, maternal factors, and African American race in the COPDGene Study

MG Foreman, L Zhang, J Murphy… - American journal of …, 2011 - atsjournals.org
Rationale: The characterization of young adults who develop late-onset diseases may
augment the detection of novel genes and promote new pathogenic insights. Methods: We …

Sex differences in airways at chest CT: results from the COPDGene cohort

SP Bhatt, S Bodduluri, A Nakhmani, Y Kim… - Radiology, 2022 - pubs.rsna.org
Background The prevalence of chronic obstructive pulmonary disease (COPD) in women is
fast approaching that in men, and women experience greater symptom burden. Although …

Particulate matter in cigarette smoke alters iron homeostasis to produce a biological effect

AJ Ghio, ED Hilborn, JG Stonehuerner… - American journal of …, 2008 - atsjournals.org
Rationale: Lung injury after cigarette smoking is related to particle retention. Iron
accumulates with the deposition of these particles. Objectives: We tested the postulate that …