Oxidative stress (OS) due to an imbalance between reactive oxygen species (ROS) and
antioxidants has been established as an important factor that can negatively affect the …

BACKGROUND A normal chromosomal constitution defined through PGT-A assessing all
chromosomes on trophectoderm (TE) biopsies represents the strongest predictor of embryo …

BACKGROUND IVF for the treatment of infertility offers unique opportunities to observe
human preimplantation development. Progress in time-lapse technology (TLT) and …

Assessing and selecting the most viable embryos for transfer is an essential part of in vitro
fertilization (IVF). In recent years, several approaches have been made to improve and …

SUMMARY ANSWER: The present ESHRE document provides 11 recommendations on
how to introduce TLT in the IVF laboratory. WHAT IS KNOWN ALREADY: Studies have been …

STUDY QUESTION Does maternal ageing impact early and late morphokinetic and cellular
processes of human blastocyst formation? SUMMARY ANSWER Maternal ageing …

STUDY QUESTION Which processes and transcription factors specify the first and second
lineage segregation events during human preimplantation development? SUMMARY …

The main goal of assisted reproductive technology (ART) is to achieve a healthy singleton
live birth after the transfer of one embryo. A major objective of IVF scientists has always been …

High quality label-free imaging of oocytes and early embryos is essential for accurate
assessment of their developmental potential, a key element of assisted reproduction …

Research question What is the intra-and inter-centre reliability in embryo grading performed
according to the Istanbul Consensus across several IVF clinics? Design Forty Day 3 …