Multiple factors combined are currently recognized as contributors to cognitive decline. The
main independent risk factor for cognitive impairment and dementia is advanced age …

The increasing number of people with dementia globally illustrates the urgent need to
reduce dementia's scale and impact. Lifetime social participation may affect dementia risk by …

Alzheimer's disease (AD) is the most common cause of dementia worldwide, but the
molecular and cellular mechanisms underlying cognitive impairment remain poorly …

Alzheimer's disease is the leading cause of dementia worldwide, but the cellular pathways
that underlie its pathological progression across brain regions remain poorly understood …

Social isolation and loneliness are serious yet underappreciated public health risks that
affect a significant portion of the older adult population. Approximately one-quarter of …

Background: The Religious Orders Study and Rush Memory and Aging Project are both
ongoing longitudinal clinical-pathologic cohort studies of aging and Alzheimer's disease …

British Psychology Society Textbook of the Year 2020 Why do people who are more socially
connected live longer and have better health than those who are socially isolated? Why are …

Background: There is some evidence to suggest that social isolation may be associated with
poor cognitive function in later life. However, findings are inconsistent and there is wide …

Background: The sudden and drastic changes due to the Coronavirus Disease 19 (COVID-
19) pandemic have impacted people's physical and mental health. Clinically-vulnerable …

It has been reported that social engagement may be associated with dementia risk. We
searched PubMed, EMBASE, PsycINFO, CINAHL, LILACS, Biomed Central, Scopus, and …