[HTML][HTML] Mitochondrial dysfunction: a fatal blow in depression

Y Song, H Cao, C Zuo, Z Gu, Y Huang, J Miao… - Biomedicine & …, 2023 - Elsevier
Mitochondria maintain the normal physiological function of nerve cells by producing
sufficient cellular energy and performing crucial roles in maintaining the metabolic balance …

Intracerebral hemorrhage, oxidative stress, and antioxidant therapy

X Duan, Z Wen, H Shen, M Shen… - Oxidative medicine and …, 2016 - Wiley Online Library
Hemorrhagic stroke is a common and severe neurological disorder and is associated with
high rates of mortality and morbidity, especially for intracerebral hemorrhage (ICH) …

Restoring cellular energetics promotes axonal regeneration and functional recovery after spinal cord injury

Q Han, Y **e, JD Ordaz, AJ Huh, N Huang, W Wu… - Cell metabolism, 2020 - cell.com
Axonal regeneration in the central nervous system (CNS) is a highly energy-demanding
process. Extrinsic insults and intrinsic restrictions lead to an energy crisis in injured axons …

Metabolic reprogramming during neuronal differentiation

M Agostini, F Romeo, S Inoue… - Cell Death & …, 2016 - nature.com
Newly generated neurons pass through a series of well-defined developmental stages,
which allow them to integrate into existing neuronal circuits. After exit from the cell cycle …

Linking mitochondrial dynamics, cristae remodeling and supercomplex formation: How mitochondrial structure can regulate bioenergetics

N Baker, J Patel, M Khacho - Mitochondrion, 2019 - Elsevier
The dynamic and fluid nature of mitochondria allows for modifications in mitochondrial
shape, connectivity and cristae architecture. The precise balance of mitochondrial dynamics …

Mitochondria as a target for neuroprotection: role of methylene blue and photobiomodulation

L Yang, H Youngblood, C Wu, Q Zhang - Translational neurodegeneration, 2020 - Springer
Mitochondrial dysfunction plays a central role in the formation of neuroinflammation and
oxidative stress, which are important factors contributing to the development of brain …

The interplay of axonal energy homeostasis and mitochondrial trafficking and anchoring

ZH Sheng - Trends in cell biology, 2017 - cell.com
Mitochondria are key cellular power plants essential for neuronal growth, survival, function,
and regeneration after injury. Given their unique morphological features, neurons face …

Facilitation of axon regeneration by enhancing mitochondrial transport and rescuing energy deficits

B Zhou, P Yu, MY Lin, T Sun, Y Chen… - Journal of Cell Biology, 2016 - rupress.org
Mitochondria are cellular power plants that supply ATP essential for neuron growth, survival,
and regeneration (Nicholls an d Budd, 2000). Because of their extremely varied …

Mitochondrial function in spinal cord injury and regeneration

PG Slater, ME Domínguez-Romero, M Villarreal… - Cellular and Molecular …, 2022 - Springer
Many people around the world suffer from some form of paralysis caused by spinal cord
injury (SCI), which has an impact on quality and life expectancy. The spinal cord is part of …

Upregulation of Ca2+-binding proteins contributes to VTA dopamine neuron survival in the early phases of Alzheimer's disease in Tg2576 mice

L La Barbera, A Nobili, E Cauzzi, I Paoletti… - Molecular …, 2022 - Springer
Background Recent clinical and experimental studies have highlighted the involvement of
Ventral Tegmental Area (VTA) dopamine (DA) neurons for the early pathogenesis of …