Mechanisms of deep brain stimulation

TM Herrington, JJ Cheng… - Journal of …, 2016 - journals.physiology.org
Deep brain stimulation (DBS) is widely used for the treatment of movement disorders
including Parkinson's disease, essential tremor, and dystonia and, to a lesser extent, certain …

Beta-band oscillations—signalling the status quo?

AK Engel, P Fries - Current opinion in neurobiology, 2010 - Elsevier
In this review, we consider the potential functional role of beta-band oscillations, which at
present is not yet well understood. We discuss evidence from recent studies on top-down …

Concurrent activation of striatal direct and indirect pathways during action initiation

G Cui, SB Jun, X **, MD Pham, SS Vogel… - Nature, 2013 - nature.com
The basal ganglia are subcortical nuclei that control voluntary actions, and they are affected
by a number of debilitating neurological disorders,,,. The prevailing model of basal ganglia …

Spatially compact neural clusters in the dorsal striatum encode locomotion relevant information

G Barbera, B Liang, L Zhang, CR Gerfen, E Culurciello… - Neuron, 2016 - cell.com
An influential striatal model postulates that neural activities in the striatal direct and indirect
pathways promote and inhibit movement, respectively. Normal behavior requires …

Neurophysiological mechanisms of deep brain stimulation across spatiotemporal resolutions

WJ Neumann, LA Steiner, L Milosevic - Brain, 2023 - academic.oup.com
Deep brain stimulation is a neuromodulatory treatment for managing the symptoms of
Parkinson's disease and other neurological and psychiatric disorders. Electrodes are …

New insights into the relationship between dopamine, beta oscillations and motor function

N Jenkinson, P Brown - Trends in neurosciences, 2011 - cell.com
Synchronised neuronal oscillations at beta frequencies are prevalent in the human motor
system, but their function is unclear. In this Opinion article, we propose that the levels of beta …

The functional role of beta oscillations in Parkinson's disease

S Little, P Brown - Parkinsonism & related disorders, 2014 - Elsevier
Summary Modulations of beta oscillations (13–30 Hz) during normal motor control suggest
that they may act to promote current motor set at the expense of new movements. These …

Behavioral theories and the neurophysiology of reward

W Schultz - Annu. Rev. Psychol., 2006 - annualreviews.org
The functions of rewards are based primarily on their effects on behavior and are less
directly governed by the physics and chemistry of input events as in sensory systems …

Oscillations and the basal ganglia: motor control and beyond

JS Brittain, P Brown - Neuroimage, 2014 - Elsevier
Oscillations form a ubiquitous feature of the central nervous system. Evidence is accruing
from cortical and sub-cortical recordings that these rhythms may be functionally important …

Pathological synchronisation in the subthalamic nucleus of patients with Parkinson's disease relates to both bradykinesia and rigidity

AA Kühn, A Tsui, T Aziz, N Ray, C Brücke… - Experimental …, 2009 - Elsevier
Parkinson's disease (PD) is associated with exaggerated oscillatory synchrony in the basal
ganglia at frequencies over 8–35 Hz. Studies have demonstrated a suppression of local field …