Mechanisms of deep brain stimulation
TM Herrington, JJ Cheng… - Journal of …, 2016 - journals.physiology.org
Deep brain stimulation (DBS) is widely used for the treatment of movement disorders
including Parkinson's disease, essential tremor, and dystonia and, to a lesser extent, certain …
including Parkinson's disease, essential tremor, and dystonia and, to a lesser extent, certain …
Beta-band oscillations—signalling the status quo?
In this review, we consider the potential functional role of beta-band oscillations, which at
present is not yet well understood. We discuss evidence from recent studies on top-down …
present is not yet well understood. We discuss evidence from recent studies on top-down …
Concurrent activation of striatal direct and indirect pathways during action initiation
The basal ganglia are subcortical nuclei that control voluntary actions, and they are affected
by a number of debilitating neurological disorders,,,. The prevailing model of basal ganglia …
by a number of debilitating neurological disorders,,,. The prevailing model of basal ganglia …
Spatially compact neural clusters in the dorsal striatum encode locomotion relevant information
An influential striatal model postulates that neural activities in the striatal direct and indirect
pathways promote and inhibit movement, respectively. Normal behavior requires …
pathways promote and inhibit movement, respectively. Normal behavior requires …
Neurophysiological mechanisms of deep brain stimulation across spatiotemporal resolutions
Deep brain stimulation is a neuromodulatory treatment for managing the symptoms of
Parkinson's disease and other neurological and psychiatric disorders. Electrodes are …
Parkinson's disease and other neurological and psychiatric disorders. Electrodes are …
New insights into the relationship between dopamine, beta oscillations and motor function
Synchronised neuronal oscillations at beta frequencies are prevalent in the human motor
system, but their function is unclear. In this Opinion article, we propose that the levels of beta …
system, but their function is unclear. In this Opinion article, we propose that the levels of beta …
The functional role of beta oscillations in Parkinson's disease
Summary Modulations of beta oscillations (13–30 Hz) during normal motor control suggest
that they may act to promote current motor set at the expense of new movements. These …
that they may act to promote current motor set at the expense of new movements. These …
Behavioral theories and the neurophysiology of reward
W Schultz - Annu. Rev. Psychol., 2006 - annualreviews.org
The functions of rewards are based primarily on their effects on behavior and are less
directly governed by the physics and chemistry of input events as in sensory systems …
directly governed by the physics and chemistry of input events as in sensory systems …
Oscillations and the basal ganglia: motor control and beyond
Oscillations form a ubiquitous feature of the central nervous system. Evidence is accruing
from cortical and sub-cortical recordings that these rhythms may be functionally important …
from cortical and sub-cortical recordings that these rhythms may be functionally important …
Pathological synchronisation in the subthalamic nucleus of patients with Parkinson's disease relates to both bradykinesia and rigidity
Parkinson's disease (PD) is associated with exaggerated oscillatory synchrony in the basal
ganglia at frequencies over 8–35 Hz. Studies have demonstrated a suppression of local field …
ganglia at frequencies over 8–35 Hz. Studies have demonstrated a suppression of local field …