Aberrant glycans are a hallmark of cancer states. Notably, emerging evidence has
demonstrated that the diagnosis of cancers with tumour-specific glycan patterns holds great …

Fucosylation is one of the most common modifications involving oligosaccharides on
glycoproteins or glycolipids. Fucosylation comprises the attachment of a fucose residue to N …

Background The sugar-chain structures of circulating alpha-fetoprotein in patients with
hepatocellular carcinomas differ from those in patients with cirrhosis. We studied the …

Chronic infection with hepatitis B virus (HBV) is associated with the majority of
hepatocellular carcinoma (HCC). The diagnosis of HCC is usually made in the late stages of …

Mammalian alpha-fetoprotein (AFP) is classified as a member of the albuminoid gene
superfamily consisting of albumin, AFP, vitamin D (Gc) protein, and alpha-albumin …

Hepatocellular carcinoma is the 5th most common cancer in the world. Prognosis for this
disease is poor since hepatocellular carcinoma is mostly diagnosed at an advanced stage …

Hepatocellular carcinoma (HCC) represents the fifth most common cancer in the world, and
the third most frequent oncological cause of death. The incidence of HCC is on the increase …

Lectin-affinity electrophoretic separation of serum α-fetoprotein (AFP) was carried out using
AFP Differentiation Kits, which used Lens culinaris agglutinin-A (Kit L) and …

GDP-L-Fuc: N-acetyl-β-D-glucosaminide α1-6-fucosyltransferase (α1-6FucT) catalyzes the
transfer of fucose from GDP-Fuc to N-linked type complex glycoproteins. This enzyme was …

Publisher Summary This chapter focuses on human protein and draw analogies to animal
models whenever it seems appropriate. A particular effort is made to summarize any findings …