Long-term cardiometabolic disease risk in women with PCOS: a systematic review and meta-analysis

V Wekker, L Van Dammen, A Koning… - Human reproduction …, 2020 - academic.oup.com
BACKGROUND Polycystic ovary syndrome (PCOS) is associated with cardiometabolic
disease, but recent systematic reviews and meta-analyses of longitudinal studies that …

Risk factors for type 2 diabetes mellitus: an exposure-wide umbrella review of meta-analyses

V Bellou, L Belbasis, I Tzoulaki, E Evangelou - PloS one, 2018 - journals.plos.org
Background Type 2 diabetes mellitus (T2DM) is a global epidemic associated with
increased health expenditure, and low quality of life. Many non-genetic risk factors have …

A narrative review on plasminogen activator inhibitor-1 and its (patho) physiological role: to target or not to target?

M Sillen, PJ Declerck - International journal of molecular sciences, 2021 - mdpi.com
Plasminogen activator inhibitor-1 (PAI-1) is the main physiological inhibitor of plasminogen
activators (PAs) and is therefore an important inhibitor of the plasminogen/plasmin system …

[HTML][HTML] The problem of wound healing in diabetes—from molecular pathways to the design of an animal model

M Mieczkowski, B Mrozikiewicz-Rakowska… - International journal of …, 2022 - mdpi.com
Chronic wounds are becoming an increasingly common clinical problem due to an aging
population and an increased incidence of diabetes, atherosclerosis, and venous …

Recent advances in biosensor technology in assessment of early diabetes biomarkers

A Salek-Maghsoudi, F Vakhshiteh, R Torabi… - Biosensors and …, 2018 - Elsevier
Discovery of biosensors has acquired utmost importance in the field of healthcare. Recent
advances in biological techniques and instrumentation involving nanomaterials, surface …

Dietary inflammatory potential in relation to the gut microbiome: results from a cross-sectional study

J Zheng, KL Hoffman, JS Chen, N Shivappa… - British Journal of …, 2020 - cambridge.org
Diet has direct and indirect effects on health through inflammation and the gut microbiome.
We investigated total dietary inflammatory potential via the literature-derived index (Dietary …

Association between plasminogen activator inhibitor-1 and cardiovascular events: a systematic review and meta-analysis

RG Jung, P Motazedian, FD Ramirez, T Simard… - Thrombosis journal, 2018 - Springer
Background Small studies have implicated plasminogen activator inhibitor-1 (PAI-1) as a
predictor of cardiovascular events; however, these findings have been inconsistent. We …

Circulating biomarkers for cardiovascular disease risk prediction in patients with cardiovascular disease

YK Wong, HF Tse - Frontiers in cardiovascular medicine, 2021 - frontiersin.org
Cardiovascular disease (CVD) is the leading cause of death globally. Risk assessment is
crucial for identifying at-risk individuals who require immediate attention as well as to guide …

Causal effect of plasminogen activator inhibitor type 1 on coronary heart disease

C Song, S Burgess, JD Eicher… - Journal of the …, 2017 - ahajournals.org
Background Plasminogen activator inhibitor type 1 (PAI‐1) plays an essential role in the
fibrinolysis system and thrombosis. Population studies have reported that blood PAI‐1 levels …

Role of PAI-1 in hepatic steatosis and dyslipidemia

JA Levine, C Oleaga, M Eren, AP Amaral, M Shang… - Scientific reports, 2021 - nature.com
Abstract Plasminogen activator inhibitor 1 (PAI-1) is a functional biomarker of the metabolic
syndrome. Previous studies have demonstrated that PAI-1 is a mechanistic contributor to …