An ultralow background substrate for protein microarray technology

H Feng, Q Zhang, H Ma, B Zheng - Analyst, 2015 - pubs.rsc.org
We herein report an ultralow background substrate for protein microarrays. Conventional
protein microarray substrates often suffer from non-specific protein adsorption and …

Limitations of label-free sensors in serum based molecular diagnostics

MM Varma - arxiv preprint arxiv:1505.01032, 2015 - arxiv.org
Immunoassay formats applicable for clinical or point-of-care diagnostics fall into two broad
classes. One which uses labeled secondary antibodies for signal transduction and the other …

Microarray substrate, microarray, microfluidic system and methods for preparing the same

B Zheng, H Feng - US Patent 9,897,602, 2018 - Google Patents
A microarray substrate including a piece of fluoropolymer whose surface is modified with
polydopamine, in which the polydopamine forms an array of microspots on the surface of the …

Kinetic Analysis of Biomolecular Interactions Using Label-Free Biosensors

YS Sun, XD Zhu - Instrumentation Science & Technology, 2015 - Taylor & Francis
One key advantage of label-free biosensors involves the monitoring of binding between
biomolecules. However, a number of experimental artifacts may lead to complicated real …

Novel Substrates for Microarrays

D Guo, H Wu, L Wu, B Zheng - Small Molecule Microarrays: Methods and …, 2017 - Springer
In the microarray platform, the surface substrate is critical to the result quality in terms of
signal consistency and detection sensitivity. Traditional substrates such as glass and …