Background: Atopic dermatitis is a common inflammatory skin disorder that affects up to 15–
20% of the population and is characterized by recurrent eczematous lesions with intense …

Over the past decades, genome-wide association studies (GWAS) have identified thousands
of phenotype-associated DNA sequence variants for potential explanations of inter …

Introduction: The complex genetic diversity among human populations results from an
assortment of factors acting at various sequential levels, including mutations, population …

Atopic dermatitis (AD) is an inflammatory skin disorder affecting up to 20% of the paediatric
population worldwide. AD patients commonly exhibit dry skin and pruritus and are at a …

T cells expressing the cutaneous lymphocyte antigen (CLA) mediate pathogenic
inflammation in atopic dermatitis (AD). The molecular alterations contributing to their …

Variants of transcription factor binding sites (TFBSs) constitute an important part of the
human genome. Current evidence demonstrates close links between nucleotides within …

Background Genetic variation influences both chromatin accessibility, assessed in
chromatin accessibility quantitative trait loci (caQTL) studies, and gene expression …

Atopic dermatitis is the most common chronic inflammatory skin disorder, affecting up to 20%
of children and 10% of adults in developed countries. The pathophysiology of atopic …

Atopic dermatitis (AD) or atopic eczema is an increasingly manifested inflammatory skin
disorder of complex etiology which is modulated by both extrinsic and intrinsic factors. The …

To date, the complex picture of atopic dermatitis (AD) has not yet been fully clarified, despite
the important prevalence of this disease in the pediatric population (20%) and the possibility …