Sulfinate derivatives: dual and versatile partners in organic synthesis

J Aziz, S Messaoudi, M Alami, A Hamze - Organic & Biomolecular …, 2014 - pubs.rsc.org
Sulfinic acids and their salts have recently emerged as versatile coupling partners to
efficiently access a wide variety of hetero-and carbocyclic compounds, under relatively mild …

Direct synthesis of sulfenamides, sulfinamides, and sulfonamides from thiols and amines

Y Cao, S Abdolmohammadi, R Ahmadi, A Issakhov… - RSC …, 2021 - pubs.rsc.org
Needless to say that organosulfur compounds with sulfur–nitrogen bonds have found
various applications in diverse fields such as pharmaceuticals, agrochemicals, polymers …

Synthesis of sulfonamides via I 2-mediated reaction of sodium sulfinates with amines in an aqueous medium at room temperature

X Pan, J Gao, J Liu, J Lai, H Jiang, G Yuan - Green Chemistry, 2015 - pubs.rsc.org
An efficient I2-mediated approach for the synthesis of sulfonamides at room temperature
using water as the solvent has been developed. This method for the synthesis of …

Oxidative cross-coupling of thiols for S–X (X= S, N, O, P, and C) bond formation: mechanistic aspects

HY Jang - Organic & Biomolecular Chemistry, 2021 - pubs.rsc.org
This review focuses on the reactive intermediates (disulfides, sulfenyl halides, thiyl radicals,
sulfenium cations, and metal–organosulfur species) and the mechanisms of the recently …

Oxidative coupling with S–N bond formation

OM Mulina, AI Ilovaisky… - European Journal of …, 2018 - Wiley Online Library
Oxidative strategies are a powerful tool in organic synthesis for the formation of heteroatom–
heteroatom, carbon–heteroatom, and carbon–carbon bonds. Among these processes the …

Recent advances in biological active sulfonamide based hybrid compounds part C: Multicomponent sulfonamide hybrids

R Ghomashi, S Ghomashi, H Aghaei… - Current Medicinal …, 2023 - benthamdirect.com
Sulfonamides, with the general formula R-SO2NR1R2, have attracted great attention since
the early discovery of sulfonamide-containing antibacterial drugs. The combinations of …

TBAI-catalyzed selective synthesis of sulfonamides and β-aryl sulfonyl enamines: coupling of arenesulfonyl chlorides and sodium sulfinates with tert-amines

H Jiang, X Tang, Z Xu, H Wang, K Han… - Organic & …, 2019 - pubs.rsc.org
A simple, practical and metal-free method has been developed for the synthesis of
sulfonamides and β-arylsulfonyl enamines via the selective cleavage of C–N and C–H …

Sulfonamide synthesis under green conditions

S Mondal - Synthetic Communications, 2021 - Taylor & Francis
Sulfonamide moiety is the backbone of various antimicrobial, anticancer, antiglaucoma,
anticonvulsant, uricosuric agents, and numerous other drugs. The age-old demand of …

Preparation of Sulfonyl Chlorides by Oxidative Chlorination of Thiols and Disulfides using HNO3/HCl/O2 in a Flow Reactor

N Sulzer, D Polterauer, CA Hone, CO Kappe - ChemSusChem, 2024 - Wiley Online Library
A continuous flow metal‐free protocol for the synthesis of sulfonyl chlorides from thiols and
disulfides in the presence of nitric acid, hydrochloric acid and oxygen was developed. The …

The photoredox-catalyzed hydrosulfamoylation of styrenes and its application in the novel synthesis of naratriptan

M Zhang, M Chen, X Ding, J Kang, Y Gao… - Chemical …, 2021 - pubs.rsc.org
The hydrosulfamoylation of diverse aryl olefins provides facile access to alkylsulfonamides.
Here we report a novel protocol utilizing radical-mediated addition and a thiol-assisted …