Parenteral administration is one of the most commonly used drug delivery routes for
nanoparticle-based dosage forms, such as lipid-based and polymeric nanoparticles. For the …

Binary co-amorphous systems (CAMS) are a type of solid dispersion containing an active
pharmaceutical ingredient (API) and small molecule excipients. The properties of these …

The central composite design is the most commonly used fractional factorial design used in
the response surface model. In this design, the center points are augmented with a group of …

Liposomes constitute the most exploited drug-nanocarrier with several liposomal drugs on
the market. Microfluidic-based preparation methods stand up as a promising approach with …

Vegetable oil refineries wastewater poses significant challenges to treatment techniques
due to its characteristic fluctuations. In this study, a full factorial design (FFD) was applied to …

Manufacturing, an industry set in the physical world, is undergoing its digital transformation,
also known as the fourth industrial revolution. Sensors, connectivity, and platforms provide …

Abstract Box–Behnken designs (BBDs) are the very efficient response surface design which
provides information exclusively on the effect of experiment variables and overall …

An industrially feasible approach to overcome the solubility and bioavailability limitations of
poorly soluble active pharmaceutical ingredients is the development of amorphous solid …

Lipid nanocarriers have attracted a great deal of interest in the delivery of therapeutic
molecules. Despite their many advantages, compliance with quality standards and …

This research conducts a systematic literature review and case study analysis to compare
the Design of Experiments (DOE) and Active Learning (AL) methods in the context of …