Memory editing from science fiction to clinical practice
Science fiction notions of altering problematic memories are starting to become reality as
techniques emerge through which unique memories can be edited. Here we review memory …
techniques emerge through which unique memories can be edited. Here we review memory …
Memory boundaries: opening a window inspired by reconsolidation to treat anxiety, trauma-related, and addiction disorders
Pioneering research over the past two decades has shown that memories are far more
malleable than we once thought, thereby highlighting the potential for new clinical avenues …
malleable than we once thought, thereby highlighting the potential for new clinical avenues …
Evidence for incentive salience sensitization as a pathway to alcohol use disorder
The incentive salience sensitization (ISS) theory of addiction holds that addictive behavior
stems from the ability of drugs to progressively sensitize the brain circuitry that mediates …
stems from the ability of drugs to progressively sensitize the brain circuitry that mediates …
Modulation of naturalistic maladaptive memories using behavioural and pharmacological reconsolidation-interfering strategies: a systematic review and meta-analysis …
Background Consolidated memories can undergo enduring modification through retrieval-
dependent treatments that modulate reconsolidation. This represents a potentially …
dependent treatments that modulate reconsolidation. This represents a potentially …
The evidence for and against reactivation-induced memory updating in humans and nonhuman animals
Systematic investigation of reactivation-induced memory updating began in the 1960s, and
a wave of research in this area followed the seminal articulation of “reconsolidation” theory …
a wave of research in this area followed the seminal articulation of “reconsolidation” theory …
Advances in behavioral animal models of alcohol use disorder
Alcohol use disorder (AUD) is a multifaceted neuropsychiatric disease that combines
behavioral, psychosocial, and neurobiological aspects. Over the previous decade, animal …
behavioral, psychosocial, and neurobiological aspects. Over the previous decade, animal …
[HTML][HTML] Manipulating critical memory periods to treat psychiatry disorders
J Deng, X Lin, Y Zheng, S Su, X Liu, K Yuan, L Shi… - Science Bulletin, 2023 - Elsevier
The persistence of pathological memory is the basis of several psychiatric disorders.
Memory retrieval induces “reconsolidation”, a time interval during which the original memory …
Memory retrieval induces “reconsolidation”, a time interval during which the original memory …
Learning processes in relapse to alcohol use: lessons from animal models
Rationale Alcohol use is reliably preceded by discrete and contextual stimuli which, through
diverse learning processes, acquire the capacity to promote alcohol use and relapse to …
diverse learning processes, acquire the capacity to promote alcohol use and relapse to …
Blocking μ-opioid receptors attenuates reinstatement of responding to an alcohol-predictive conditioned stimulus through actions in the ventral hippocampus
MR LeCocq, P Chander, N Chaudhri - Neuropsychopharmacology, 2023 - nature.com
The µ-opioid system is involved in the reinstatement of responding that is immediately
evoked by alcohol-predictive cues. The extent of its involvement in reinstatement observed …
evoked by alcohol-predictive cues. The extent of its involvement in reinstatement observed …
Behavioral, neurobiological, and neurochemical mechanisms of ethanol self-administration: A translational review
AA Vena, SL Zandy, RU Cofresí… - Pharmacology & …, 2020 - Elsevier
Alcohol use disorder has multiple characteristics including excessive ethanol consumption,
impaired control over drinking behaviors, craving and withdrawal symptoms, compulsive …
impaired control over drinking behaviors, craving and withdrawal symptoms, compulsive …