A survey on applications of deep learning in microscopy image analysis

Z Liu, L **, J Chen, Q Fang, S Ablameyko, Z Yin… - Computers in biology …, 2021 - Elsevier
Advanced microscopy enables us to acquire quantities of time-lapse images to visualize the
dynamic characteristics of tissues, cells or molecules. Microscopy images typically vary in …

Next-generation lineage tracing and fate map** to interrogate development

S VanHorn, SA Morris - Developmental cell, 2021 - cell.com
Lineage tracing and fate map**, overlap** yet distinct disciplines to follow cells and
their progeny, have evolved rapidly over the last century. Lineage tracing aims to identify all …

Development and evaluation of a deep learning model for protein–ligand binding affinity prediction

MM Stepniewska-Dziubinska, P Zielenkiewicz… - …, 2018 - academic.oup.com
Motivation Structure based ligand discovery is one of the most successful approaches for
augmenting the drug discovery process. Currently, there is a notable shift towards machine …

Computer vision meets microfluidics: a label-free method for high-throughput cell analysis

S Zhou, B Chen, ES Fu, H Yan - Microsystems & Nanoengineering, 2023 - nature.com
In this paper, we review the integration of microfluidic chips and computer vision, which has
great potential to advance research in the life sciences and biology, particularly in the …

[HTML][HTML] Computerized cell tracking: Current methods, tools and challenges

N Emami, Z Sedaei, R Ferdousi - Visual Informatics, 2021 - Elsevier
In developmental biology, knowledge of cell structure and their (morpho) dynamic behavior,
leads to a comprehensive understanding of their conducts and the mechanisms in which …

The use of digital pathology and image analysis in clinical trials

R Pell, K Oien, M Robinson, H Pitman… - The Journal of …, 2019 - Wiley Online Library
Digital pathology and image analysis potentially provide greater accuracy, reproducibility
and standardisation of pathology‐based trial entry criteria and endpoints, alongside …

A microfluidic co-cultivation platform to investigate microbial interactions at defined microenvironments

A Burmeister, F Hilgers, A Langner… - Lab on a Chip, 2019 - pubs.rsc.org
Interspecies interactions inside microbial communities bear a tremendous diversity of
complex chemical processes that are by far not understood. Even for simplified, often …

[HTML][HTML] Controlling cell size through sizer mechanisms

G Facchetti, F Chang, M Howard - Current Opinion in Systems Biology, 2017 - Elsevier
Cell size is partly determined through coordination between cell growth and division. How
this coordination is achieved mechanistically remains mostly unknown. However …

Multidimensional contrast limited adaptive histogram equalization

V Stimper, S Bauer, R Ernstorfer, B Schölkopf… - IEEE …, 2019 - ieeexplore.ieee.org
Contrast enhancement is an important preprocessing technique for improving the
performance of downstream tasks in image processing and computer vision. Among the …

How phenotypic screening influenced drug discovery: lessons from five years of practice

D Haasen, U Schopfer, C Antczak, C Guy… - Assay and drug …, 2017 - liebertpub.com
Since 2011, phenotypic screening has been a trend in the pharmaceutical industry as well
as in academia. This renaissance was triggered by analyses that suggested that phenotypic …