Aortic dissection continues to be responsible for significant morbidity and mortality, although
recent advances in medical data assimilation and in experimental and in silico models have …

Hemodynamic factors, induced by pulsatile blood flow, play a crucial role in vascular health
and diseases, such as the initiation and progression of atherosclerosis. Computational fluid …

Although unphysiological wall shear stress (WSS) has become the consensus
hemodynamic mechanism for coronary atherosclerosis, the complex biomechanical stimulus …

Background and aims Wall shear stress (WSS) has been associated with atherogenesis and
plaque progression. The present study assessed the value of WSS analysis derived from …

Abstract Background and Objective In this paper we investigate twelve multi-
directional/topological wall shear stress (WSS) derived metrics and their relationships with …

Coronary artery atherosclerosis is a local, multifactorial, complex disease, and the leading
cause of death in the US. Complex interactions between biochemical transport and …

Abstract Wall Shear Stress (WSS) topological skeleton, composed by fixed points and the
manifolds linking them, reflects the presence of blood flow features associated to adverse …

The degeneration of the arterial wall at the basis of the ascending thoracic aortic aneurysm
(ATAA) is a complex multifactorial process, which may lead to clinical complications and …

Calcific degeneration is the most frequent type of heart valve failure, with rising incidence
due to the ageing population. The gold standard treatment to date is valve replacement …

Broadening current knowledge about the complex relationship at the blood-vessel wall
interface is a main challenge in hemodynamics research. Moving from the consideration that …