Recent trends of contrast agents in ultrasound imaging: a review of the classifications and applications

A Tarighatnia, MR Fouladi, ND Nader… - Materials …, 2022 - pubs.rsc.org
Ultrasound (US) imaging, due to its capabilities of real-time imaging, portability, low cost and
favorable safety, is frequently used as a diagnostic modality for the visualization of different …

From anatomy to functional and molecular biomarker imaging and therapy: ultrasound is safe, ultrafast, portable, and inexpensive

S Wang, JA Hossack, AL Klibanov - Investigative radiology, 2020 - journals.lww.com
Ultrasound is the most widely used medical imaging modality worldwide. It is abundant,
extremely safe, portable, and inexpensive. In this review, we consider some of the current …

In vitro characterization and in vivo ultrasound molecular imaging of nucleolin-targeted microbubbles

H Zhang, ES Ingham, MKJ Gagnon, LM Mahakian… - Biomaterials, 2017 - Elsevier
Nucleolin (NCL) plays an important role in tumor vascular development. An increased
endothelial expression level of NCL has been related to cancer aggressiveness and …

BR55 Ultrasound Molecular Imaging of Clear Cell Renal Cell Carcinoma Reflects Tumor Vascular Expression of VEGFR-2 in a Patient-Derived Xenograft Model

J Courcier, I Leguerney, B Benatsou, S Pochon… - International Journal of …, 2023 - mdpi.com
Standard imaging cannot reliably predict the nature of renal tumors. Among malignant renal
tumors, clear cell renal cell carcinoma (ccRCC) is the most common histological subtype, in …

[HTML][HTML] Ultrasound molecular imaging as a non-invasive companion diagnostic for netrin-1 interference therapy in breast cancer

J Wischhusen, KE Wilson, JG Delcros… - Theranostics, 2018 - ncbi.nlm.nih.gov
In ultrasound molecular imaging (USMI), ligand-functionalized microbubbles (MBs) are used
to visualize vascular endothelial targets. Netrin-1 is upregulated in 60% of metastatic breast …

Ultrasound molecular imaging with BR55, a predictive tool of antiangiogenic treatment efficacy in a chemo-induced mammary tumor model

A Helbert, M Von Wronski, D Colevret… - Investigative …, 2020 - journals.lww.com
Objectives The aim of this study was to evaluate the added value of ultrasound molecular
imaging of the vascular growth factor receptor 2 (VEGFR2) expression, using the clinical …

Pathogenic CD8+ T Cells Cause Increased Levels of VEGF-A in Experimental Malaria-Associated Acute Respiratory Distress Syndrome, but Therapeutic VEGFR …

TT Pham, M Verheijen, L Vandermosten… - Frontiers in Cellular …, 2017 - frontiersin.org
Malaria is a severe disease and kills over 400,000 people each year. Malarial complications
are the main cause of death and include cerebral malaria and malaria-associated acute …

Contrast-enhanced ultrasound with VEGFR2-targeted microbubbles for monitoring regorafenib therapy effects in experimental colorectal adenocarcinomas in rats with …

RS Eschbach, DA Clevert, H Hirner-Eppeneder… - PLoS …, 2017 - journals.plos.org
Objectives To investigate contrast-enhanced ultrasound (CEUS) with VEGFR2-targeted
microbubbles for monitoring therapy effects of regorafenib on experimental colon …

3-D longitudinal imaging of tumor angiogenesis in mice in vivo using ultrafast Doppler tomography

C Demené, T Payen, A Dizeux, G Barrois… - Ultrasound in Medicine …, 2019 - Elsevier
Angiogenesis, the formation of new vessels, is one of the key mechanisms in tumor
development and an appealing target for therapy. Non-invasive, high-resolution, high …

Molecular imaging of angiogenesis in cardiac regeneration

L Mandic, D Traxler, A Gugerell, K Zlabinger… - Current cardiovascular …, 2016 - Springer
Abstract Purpose of Review Myocardial infarction (MI) leading to heart failure displays an
important cause of death worldwide. Adequate restoration of blood flow to prevent this …