Human immunodeficiency virus (HIV) causes one of the most dangerous diseases—
acquired immunodeficiency syndrome (AIDS). An estimated about 40 million people are …

Helically folded oligoamides of 8‐amino‐2‐quinolinecarboxylic acid composed of up to 41
units were prepared using optimized manual solid‐phase synthesis (SPS). The high yield …

The term “privileged structure” refers to a single molecular substructure or scaffold that can
serve as a starting point for high‐affinity ligands for more than one receptor type. In this …

The use of synthetic chemicals to selectively interfere with chromatin and the chromatin-
bound proteome represents a great opportunity for pharmacological intervention. Recently …

Cystobactamids are aromatic oligoamides that exert their natural antibacterial properties by
inhibition of bacterial gyrases. Such aromatic oligoamides were proposed to inhibit α‐helix …

The extensive research work in the exhilarating area of foldamers (artificial oligomers
possessing well-defined conformation in solution) has shown them to be promising …

Fluorine, the tiny robust atom, with its unique features has captured the attention of scientists
in recent times, especially in drug discovery with its integration in small molecules, peptides …

An amphiphilic segmented polyurethane (F-PU-S), with pendant sulfate groups and a
flexible hydrocarbon backbone, exhibits intrachain H-bonding-reinforced folding and …

Foldamers are non-natural oligomers that mimic the structural behaviour of natural peptides,
proteins and nucleotides by folding into a well-defined 3D conformation in solution. Since …

A biotinylated helical aromatic oligoamide foldamer equivalent in size to a 24mer peptide
was designed without any prejudice other than to display various polar and hydrophobic …