Potential epigenetic mechanism in non-alcoholic fatty liver disease

C Sun, JG Fan, L Qiao - International journal of molecular sciences, 2015 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is characterized by excessive fat accumulation in
the liver. It ranges from simple steatosis to its more aggressive form, non-alcoholic …

Transcriptomic and epigenetic changes in early liver steatosis associated to obesity: effect of dietary methyl donor supplementation

P Cordero, J Campion, FI Milagro… - Molecular genetics and …, 2013 - Elsevier
Non-alcoholic fatty liver disease is a primary hepatic manifestation of obesity and an
important adverse metabolic syndrome trait. Animal models of diet-induced obesity promote …

The effect of high-fat diet on rat's mood, feeding behavior and response to stress

S Aslani, N Vieira, F Marques, PS Costa… - Translational …, 2015 - nature.com
An association between obesity and depression has been indicated in studies addressing
common physical (metabolic) and psychological (anxiety, low self-esteem) outcomes. Of …

Methyl donor supplementation in rats reverses the deleterious effect of maternal separation on depression-like behaviour

L Paternain, E Martisova, J Campión… - Behavioural brain …, 2016 - Elsevier
Adverse early life events are associated with altered stress responsiveness and metabolic
disturbances in the adult life. Dietary methyl donor supplementation could be able to reverse …

Effects of maternal high-fat diet on fetal growth, placental nutrient transporters and circular RNA expression profiles

T He, Q Chen, Z Yuan, Y Yang, K Cao, J Luo… - Food & Function, 2023 - pubs.rsc.org
Epidemiological and experimental studies suggest that there is a strong correlation between
maternal high-fat diet and fetal–placental development. The current study aims to investigate …

Prenatal stress increases the obesogenic effects of a high-fat-sucrose diet in adult rats in a sex-specific manner

L Paternain, AL De La Garza, MA Batlle, FI Milagro… - Stress, 2013 - Taylor & Francis
Stress during pregnancy can induce metabolic disorders in adult offspring. To analyze the
possible differential response to a high-fat-sucrose (HFS) diet in offspring affected by …

Transcriptomic and epigenetic changes in the hypothalamus are involved in an increased susceptibility to a high-fat-sucrose diet in prenatally stressed female rats

L Paternain, MA Batlle, AL De la Garza, FI Milagro… - …, 2012 - karger.com
Disturbances in the prenatal period are linked to metabolic disorders in adulthood, implying
the hypothalamic systems of appetite and energy balance regulation. In order to analyze the …

A cafeteria diet modifies the response to chronic variable stress in rats

N Zeeni, C Daher, G Fromentin, D Tomé, N Darcel… - Stress, 2013 - Taylor & Francis
Stress is known to lead to metabolic and behavioral changes. To study the possible
relationships between stress and dietary intake, male Sprague-Dawley rats were fed one of …

[HTML][HTML] A polyphenol-rich Calafate (Berberis microphylla) extract rescues glucose tolerance in mice fed with cafeteria diet

J Soto-Covasich, M Reyes-Farias, RF Torres… - Journal of Functional …, 2020 - Elsevier
The establishment of a chronic inflammatory state in the adipose tissue contributes to
obesity-associated insulin resistance. Hence, disrupting the inflammatory response elicited …

[HTML][HTML] Effect of chronic psychosocial stress on nonalcoholic steatohepatitis in mice

B Czech, ID Neumann, M Müller, SO Reber… - … journal of clinical and …, 2013 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) is characterized by hepatic lipid accumulation
which may progress towards inflammation (nonalcoholic steatohepatitis (NASH)). NAFLD is …