The next phase of SARS-CoV-2 surveillance: real-time molecular epidemiology

BB Oude Munnink, N Worp, DF Nieuwenhuijse… - Nature medicine, 2021 - nature.com
The current coronavirus disease 2019 (COVID-19) pandemic is the first to apply whole-
genome sequencing near to real time, with over 2 million severe acute respiratory syndrome …

The continued threat of emerging flaviviruses

TC Pierson, MS Diamond - Nature microbiology, 2020 - nature.com
Flaviviruses are vector-borne RNA viruses that can emerge unexpectedly in human
populations and cause a spectrum of potentially severe diseases including hepatitis …

Pathways to zoonotic spillover

RK Plowright, CR Parrish, H McCallum… - Nature Reviews …, 2017 - nature.com
Zoonotic spillover, which is the transmission of a pathogen from a vertebrate animal to a
human, presents a global public health burden but is a poorly understood phenomenon …

Towards a genomics-informed, real-time, global pathogen surveillance system

JL Gardy, NJ Loman - Nature Reviews Genetics, 2018 - nature.com
Abstract The recent Ebola and Zika epidemics demonstrate the need for the continuous
surveillance, rapid diagnosis and real-time tracking of emerging infectious diseases. Fast …

Zika virus infection—after the pandemic

D Musso, AI Ko, D Baud - New England Journal of Medicine, 2019 - Mass Medical Soc
Zika Virus and Its Associated Diseases Zika is a mosquito-borne flavivirus that can cause
congenital defects, including microcephaly. Although most Zika virus infections are …

Rapid SARS-CoV-2 whole-genome sequencing and analysis for informed public health decision-making in the Netherlands

BB Oude Munnink, DF Nieuwenhuijse, M Stein… - Nature Medicine, 2020 - nature.com
In late December 2019, a cluster of cases of pneumonia of unknown etiology were reported
linked to a market in Wuhan, China. The causative agent was identified as the species …

Tracking virus outbreaks in the twenty-first century

ND Grubaugh, JT Ladner, P Lemey, OG Pybus… - Nature …, 2019 - nature.com
Emerging viruses have the potential to impose substantial mortality, morbidity and economic
burdens on human populations. Tracking the spread of infectious diseases to assist in their …

[HTML][HTML] Brain-region-specific organoids using mini-bioreactors for modeling ZIKV exposure

X Qian, HN Nguyen, MM Song, C Hadiono, SC Ogden… - Cell, 2016 - cell.com
Cerebral organoids, three-dimensional cultures that model organogenesis, provide a new
platform to investigate human brain development. High cost, variability, and tissue …

The Brazilian Zika virus strain causes birth defects in experimental models

FR Cugola, IR Fernandes, FB Russo, BC Freitas… - Nature, 2016 - nature.com
Zika virus (ZIKV) is an arbovirus belonging to the genus Flavivirus (family Flaviviridae) and
was first described in 1947 in Uganda following blood analyses of sentinel Rhesus …

Rapid SARS-CoV-2 whole-genome sequencing and analysis for informed public health decision-making in the Netherlands

BBO Munnink, DF Nieuwenhuijse, M Stein… - Nature medicine, 2020 - go.gale.com
In late December 2019, a cluster of cases of pneumonia of unknown etiology were reported
linked to a market in Wuhan, China. sup. 1. The causative agent was identified as the …