Antibiotic perturbations to the gut microbiome

SRS Fishbein, B Mahmud, G Dantas - Nature Reviews Microbiology, 2023 - nature.com
Antibiotic-mediated perturbation of the gut microbiome is associated with numerous
infectious and autoimmune diseases of the gastrointestinal tract. Yet, as the gut microbiome …

Current rates of purchasing of antibiotics without a prescription across sub-Saharan Africa; rationale and potential programmes to reduce inappropriate dispensing …

TM Sono, E Yeika, A Cook, A Kalungia… - Expert review of anti …, 2023 - Taylor & Francis
Introduction Antimicrobial resistance (AMR) is a global concern. Currently, the greatest
mortality due to AMR is in Africa. A key driver continues to be high levels of dispensing of …

ACE2 binding and antibody evasion in enhanced transmissibility of XBB. 1.5

C Yue, W Song, L Wang, F Jian, X Chen… - The Lancet Infectious …, 2023 - thelancet.com
SARS-CoV-2 subvariants BQ. 1.1 and XBB. 1 have been circulating globally with superior
growth advantages over most omicron mutants (appendix p 5). However, XBB. 1.5, a …

[HTML][HTML] Update to CDC's treatment guidelines for gonococcal infection, 2020

SS Cyr - MMWR. Morbidity and mortality weekly report, 2020 - cdc.gov
Based on review of recent evidence, CDC recommends a single 500 mg intramuscular dose
of ceftriaxone for uncomplicated gonorrhea. Treatment for coinfection with Chlamydia …

Sales of antibiotics and hydroxychloroquine in India during the COVID-19 epidemic: An interrupted time series analysis

G Sulis, B Batomen, A Kotwani, M Pai, S Gandra - PLoS medicine, 2021 - journals.plos.org
Background We assessed the impact of the coronavirus disease 2019 (COVID-19) epidemic
in India on the consumption of antibiotics and hydroxychloroquine (HCQ) in the private …

What can work and how? An overview of evidence-based interventions and delivery strategies to support health and human development from before conception to …

T Vaivada, ZS Lassi, O Irfan, RA Salam, JK Das, C Oh… - The Lancet, 2022 - thelancet.com
Progress has been made globally in improving the coverage of key maternal, newborn, and
early childhood interventions in low-income and middle-income countries, which has …

Azithromycin to Reduce Mortality—An Adaptive Cluster-Randomized Trial

KS O'Brien, AM Arzika, A Amza, R Maliki… - … England Journal of …, 2024 - Mass Medical Soc
Background Twice-yearly mass distribution of azithromycin to children is a promising
intervention to reduce childhood mortality in sub-Saharan Africa. The World Health …

Effect of oral azithromycin vs placebo on COVID-19 symptoms in outpatients with SARS-CoV-2 infection: a randomized clinical trial

CE Oldenburg, BA Pinsky, J Brogdon, C Chen, K Ruder… - Jama, 2021 - jamanetwork.com
Importance Azithromycin has been hypothesized to have activity against SARS-CoV-2.
Objective To determine whether oral azithromycin in outpatients with SARS-CoV-2 infection …

Impact of antibiotics on gut microbiome composition and resistome in the first years of life in low-to middle-income countries: A systematic review

CC Luchen, M Chibuye, R Spijker, M Simuyandi… - PLoS …, 2023 - journals.plos.org
Background Inappropriate antimicrobial usage is a key driver of antimicrobial resistance
(AMR). Low-and middle-income countries (LMICs) are disproportionately burdened by AMR …

Review on PLGA polymer based nanoparticles with antimicrobial properties and their application in various medical conditions or infections

AK Shakya, M Al-Sulaibi, RR Naik, H Nsairat, S Suboh… - Polymers, 2023 - mdpi.com
The rise in the resistance to antibiotics is due to their inappropriate use and the use of a
broad spectrum of antibiotics. This has also contributed to the development of multidrug …