Antimicrobial peptides (AMPs) are a heterogeneous class of compounds found in a variety
of organisms including humans and, so far, hundreds of these structures have been isolated …

The rise in multidrug resistant (MDR) bacteria has become a global crisis. Rapid and
accurate diagnosis of infection will facilitate antibiotic stewardship and preserve our ability to …

Bacterial infections remain a major threat to humanity and are a leading cause of death and
disability. Antimicrobial resistance has been declared as one of the top ten threats to human …

Bacterial infections have always been, and still are, a major global healthcare problem. For
accurate treatment it is of upmost importance that the location (s), severity, type of bacteria …

Antimicrobial peptides such as ubiquicidin (UBI) are believed to differentiate between
mammalian and bacterial or fungal cells. 99mTc-UBI29-41 was previously tested for …

Nuclear medicine imaging techniques offer whole body imaging for localization of number
and site of infective foci inspite of limitation of spatial resolution. The innate human immune …

To develop a novel 99mTc-labeled ubiquicidin 29-41 derivative for bacterial infection single-
photon emission computed tomography (SPECT) imaging with improved target-to-nontarget …

2-18F-fluorodeoxysorbitol (18F-FDS) has been shown to be a promising agent with high
selectivity and sensitivity in imaging bacterial infection. The objective of our study was to …

Purpose Although the data are promising from limited studies with technetium-99m
ubiquicidin (99m Tc-UBI) scintigraphy in detection of infection in humans, these studies have …

Purpose Detection of osteomyelitis beneath a diabetic foot ulcer is imperative for proper
management; however, accurate and noninvasive diagnosis of osteomyelitis remains a …