Cell signaling and transcriptional regulation of osteoblast lineage commitment, differentiation, bone formation, and homeostasis

S Zhu, W Chen, A Masson, YP Li - Cell Discovery, 2024 - nature.com
The initiation of osteogenesis primarily occurs as mesenchymal stem cells undergo
differentiation into osteoblasts. This differentiation process plays a crucial role in bone …

Synthetic extracellular matrices with function-encoding peptides

C Ligorio, A Mata - Nature reviews bioengineering, 2023 - nature.com
The communication of cells with their surroundings is mostly encoded in the epitopes of
structural and signalling proteins present in the extracellular matrix (ECM). These peptide …

[HTML][HTML] Bone morphogenetic protein-2 in development and bone homeostasis

D Halloran, HW Durbano, A Nohe - Journal of developmental biology, 2020 - mdpi.com
Bone morphogenetic proteins (BMPs) are multi-functional growth factors belonging to the
Transforming Growth Factor-Beta (TGF-β) superfamily. These proteins are essential to many …

RANKL/RANK/OPG pathway: a mechanism involved in exercise‐induced bone remodeling

M Tobeiha, MH Moghadasian, N Amin… - BioMed research …, 2020 - Wiley Online Library
Bones as an alive organ consist of about 70% mineral and 30% organic component. About
200 million people are suffering from osteopenia and osteoporosis around the world. There …

A review of the clinical side effects of bone morphogenetic protein-2

AW James, G LaChaud, J Shen, G Asatrian… - … Engineering Part B …, 2016 - liebertpub.com
Bone morphogenetic protein-2 (BMP-2) is currently the only Food and Drug Administration
(FDA)-approved osteoinductive growth factor used as a bone graft substitute. However, with …

Molecular regulation of adipogenesis and potential anti-adipogenic bioactive molecules

D Moseti, A Regassa, WK Kim - International journal of molecular …, 2016 - mdpi.com
Adipogenesis is the process by which precursor stem cells differentiate into lipid laden
adipocytes. Adipogenesis is regulated by a complex and highly orchestrated gene …

Fucoidan structure and activity in relation to anti-cancer mechanisms

G Van Weelden, M Bobiński, K Okła, WJ Van Weelden… - Marine drugs, 2019 - mdpi.com
Fucoidan is a natural derived compound found in different species of brown algae and in
some animals, that has gained attention for its anticancer properties. However, the exact …

Autologous Tooth Graft: Innovative Biomaterial for Bone Regeneration. Tooth Transformer® and the Role of Microbiota in Regenerative Dentistry. A Systematic …

AM Inchingolo, A Patano, C Di Pede… - Journal of Functional …, 2023 - mdpi.com
Different biomaterials, from synthetic products to autologous or heterologous grafts, have
been suggested for the preservation and regeneration of bone. The aim of this study is to …

Endocrine role of bone in the regulation of energy metabolism

R Zhou, Q Guo, Y **ao, Q Guo, Y Huang, C Li, X Luo - Bone research, 2021 - nature.com
Abstracts Bone mainly functions as a supportive framework for the whole body and is the
major regulator of calcium homeostasis and hematopoietic function. Recently, an increasing …

[HTML][HTML] Anti-carcinogenic glucosinolates in cruciferous vegetables and their antagonistic effects on prevention of cancers

P Soundararajan, JS Kim - Molecules, 2018 - mdpi.com
Glucosinolates (GSL) are naturally occurring β-d-thioglucosides found across the
cruciferous vegetables. Core structure formation and side-chain modifications lead to the …