Simultaneous immunization of mice with Omp31 and TF provides protection against Brucella melitensis infection
A Ghasemi, M Jeddi-Tehrani, J Mautner, MH Salari… - Vaccine, 2015 - Elsevier
Brucella vaccines consisting of live attenuated Brucella strains are currently used in
livestock, but safety concerns preclude their application in humans. Subunit vaccines have …
livestock, but safety concerns preclude their application in humans. Subunit vaccines have …
Immunization of mice with a novel recombinant molecular chaperon confers protection against Brucella melitensis infection
A Ghasemi, M Jeddi-Tehrani, J Mautner, MH Salari… - Vaccine, 2014 - Elsevier
Brucella spp. are zoonotic Gram-negative intracellular pathogens with the ability to survive
and replicate in phagocytes. It has been shown that bacterial proteins expressed abundantly …
and replicate in phagocytes. It has been shown that bacterial proteins expressed abundantly …
Production of Brucella melitensis Omp16 protein fused to the human interleukin 2 in Lactococcus lactis MG1363 toward develo** a Lactococcus-based vaccine …
M Rezaei, M Rabbani Khorasgani… - Canadian journal of …, 2020 - cdnsciencepub.com
The use of the food-grade bacterium Lactococcus lactis as a new cell factory is a promising
alternative expression system for producing a desired protein. The Omp16-IL2 fusion protein …
alternative expression system for producing a desired protein. The Omp16-IL2 fusion protein …
Vaccines and vaccine candidates against brucellosis
Brucella is a facultative intracellular pathogen, and brucellosis is commonest zoonotic
disease worldwide. Brucella species, isolated from domestic animals, are important …
disease worldwide. Brucella species, isolated from domestic animals, are important …
Identification of a new immunogenic candidate conferring protection against Brucella melitensis infection in mice
A Ghasemi, AH Zarnani, A Ghoodjani, S Rezania… - Molecular …, 2014 - Elsevier
Identification of bacterial proteins that contribute to the replication and survival of the
engulfed bacteria within phagolysosome is critical in the pathogenesis of intracellular …
engulfed bacteria within phagolysosome is critical in the pathogenesis of intracellular …
[HTML][HTML] Immunization of mice with chimeric protein-loaded aluminum hydroxide and selenium nanoparticles induces reduction of Brucella melitensis infection in mice
Purpose Due to the many problems with commercially available vaccines, the production of
effective vaccines against brucellosis is a necessity. The aim of this study was to evaluate …
effective vaccines against brucellosis is a necessity. The aim of this study was to evaluate …
Immunogenicity of Brucella Trivalent Immunogen-Containing Polyethyleneimine Nanostructure Targeted with LPS in a Mouse Model
M Iranikhah, R Nazari, M Fasihi-Ramandi… - Current …, 2024 - Springer
Brucella is a facultative intracellular gram-negative coccobacillus. It is nonsporulating and
reproduced in macrophage phagosomes. The use of nanostructures as drug and vaccine …
reproduced in macrophage phagosomes. The use of nanostructures as drug and vaccine …
[PDF][PDF] A recombinant chimera protein as a novel Brucella subunit vaccine: protective efficacy and induced immune response in BALB/c mice
Background: Brucellosis is one of the main causes of economic loss in domestic animals
due to abortions and infertility. Brucella is a facultative intracellular pathogen that survives in …
due to abortions and infertility. Brucella is a facultative intracellular pathogen that survives in …
[HTML][HTML] Optimization and efficient purification in production of Brucella melitensis recombinant HSP and TF proteins with low endotoxin contents
Background: The development of an effective subunit vaccine against brucellosis is a
research area of intense. But optimization of recombinant proteins production in Escherichia …
research area of intense. But optimization of recombinant proteins production in Escherichia …
[HTML][HTML] Immune reactivity of sera obtained from brucellosis patients and vaccinated-rabbits to a fusion protein from Brucella melitensis
Objective (s): Brucella spp. are facultative intracellular pathogens which can stay alive and
multiply in professional and nonprofessional phagocytes. Immunity against Brucella …
multiply in professional and nonprofessional phagocytes. Immunity against Brucella …