Myricetin: A dietary molecule with diverse biological activities

DK Semwal, RB Semwal, S Combrinck, A Viljoen - Nutrients, 2016 - mdpi.com
Myricetin is a common plant-derived flavonoid and is well recognised for its nutraceuticals
value. It is one of the key ingredients of various foods and beverages. The compound …

A twist of nature–the significance of atropisomers in biological systems

JE Smyth, NM Butler, PA Keller - Natural product reports, 2015 - pubs.rsc.org
Covering: up to mid-2015 Recently identified natural atropisomeric compounds with
potential medicinal applications are presented. The ability of natural receptors to possess …

Myricetin bioactive effects: Moving from preclinical evidence to potential clinical applications

Y Taheri, HAR Suleria, N Martins, O Sytar… - … medicine and therapies, 2020 - Springer
Several flavonoids have been recognized as nutraceuticals, and myricetin is a good
example. Myricetin is commonly found in plants and their antimicrobial and antioxidant …

Natural anti-inflammatory compounds as drug candidates for inflammatory bowel disease

L Duan, S Cheng, L Li, Y Liu, D Wang… - Frontiers in …, 2021 - frontiersin.org
Inflammatory bowel disease (IBD) represents chronic recurrent intestinal inflammation
resulting from various factors. Crohn's disease (CD) and ulcerative colitis (UC) have been …

Current screening methodologies in drug discovery for selected human diseases

OM Lage, MC Ramos, R Calisto, E Almeida… - Marine drugs, 2018 - mdpi.com
The increase of many deadly diseases like infections by multidrug-resistant bacteria implies
re-inventing the wheel on drug discovery. A better comprehension of the metabolisms and …

Recent advances in the synthesis of diarylheptanoids

K Sudarshan, S Yarlagadda… - Chemistry–An Asian …, 2024 - Wiley Online Library
In the quest for synthesizing biologically important natural products, medicinal chemists
embark on an endless journey. This review focuses on the reports published towards the …

Pathological tau promotes neuronal damage by impairing ribosomal function and decreasing protein synthesis

S Meier, M Bell, DN Lyons… - Journal of …, 2016 - Soc Neuroscience
One of the most common symptoms of Alzheimer's disease (AD) and related tauopathies is
memory loss. The exact mechanisms leading to memory loss in tauopathies are not yet …

Myricanol rescues dexamethasone‐induced muscle dysfunction via a sirtuin 1‐dependent mechanism

S Shen, Q Liao, J Liu, R Pan… - Journal of cachexia …, 2019 - Wiley Online Library
Background Muscle atrophy and weakness are adverse effects of high dose or the sustained
usage of glucocorticoids. Loss of mitochondria and degradation of protein are highly …

Myricetin: A significant emphasis on its anticancer potential via the modulation of inflammation and signal transduction pathways

AH Rahmani, A Almatroudi, KS Allemailem… - International Journal of …, 2023 - mdpi.com
Cancer is a major public health concern worldwide and main burden of the healthcare
system. Regrettably, most of the currently used cancer treatment approaches such as …

Natural antitubulin agents: Importance of 3, 4, 5-trimethoxyphenyl fragment

AS Negi, Y Gautam, S Alam, D Chanda… - Bioorganic & medicinal …, 2015 - Elsevier
Microtubules are polar cytoskeletal filaments assembled from head-to-tail and comprised of
lateral associations of α/β-tubulin heterodimers that play key role in various cellular …