The dynamic lung microbiome in health and disease

JG Natalini, S Singh, LN Segal - Nature Reviews Microbiology, 2023 - nature.com
New methods and technologies within the field of lung biology are beginning to shed new
light into the microbial world of the respiratory tract. Long considered to be a sterile …

Lung microbiome: new insights into the pathogenesis of respiratory diseases

R Li, J Li, X Zhou - Signal transduction and targeted therapy, 2024 - nature.com
The lungs were long thought to be sterile until technical advances uncovered the presence
of the lung microbial community. The microbiome of healthy lungs is mainly derived from the …

Microbiome and human health: current understanding, engineering, and enabling technologies

N Aggarwal, S Kitano, GRY Puah, S Kittelmann… - Chemical …, 2022 - ACS Publications
The human microbiome is composed of a collection of dynamic microbial communities that
inhabit various anatomical locations in the body. Accordingly, the coevolution of the …

Microbiota in health and diseases

K Hou, ZX Wu, XY Chen, JQ Wang, D Zhang… - Signal transduction and …, 2022 - nature.com
The role of microbiota in health and diseases is being highlighted by numerous studies
since its discovery. Depending on the localized regions, microbiota can be classified into …

Dysbiosis of the gut and lung microbiome has a role in asthma

K Hufnagl, I Pali-Schöll, F Roth-Walter… - Seminars in …, 2020 - Springer
Worldwide 300 million children and adults are affected by asthma. The development of
asthma is influenced by environmental and other exogenous factors synergizing with …

Functional effects of the microbiota in chronic respiratory disease

KF Budden, SD Shukla, SF Rehman… - The Lancet …, 2019 - thelancet.com
The composition of the lung microbiome is increasingly well characterised, with changes in
microbial diversity or abundance observed in association with several chronic respiratory …

A biodiversity hypothesis

T Haahtela - Allergy, 2019 - Wiley Online Library
Biodiversity hypothesis states that contact with natural environments enriches the human
microbiome, promotes immune balance and protects from allergy and inflammatory …

Smoking and microbiome in oral, airway, gut and some systemic diseases

C Huang, G Shi - Journal of translational medicine, 2019 - Springer
The human microbiome harbors a diverse array of microbes which establishes a mutually
beneficial relation with the host in healthy conditions, however, the dynamic homeostasis is …

Enrichment of the lung microbiome with gut bacteria in sepsis and the acute respiratory distress syndrome

RP Dickson, BH Singer, MW Newstead… - Nature …, 2016 - nature.com
Sepsis and the acute respiratory distress syndrome (ARDS) are major causes of mortality
without targeted therapies. Although many experimental and clinical observations have …

Interaction between the microbiome and TP53 in human lung cancer

KL Greathouse, JR White, AJ Vargas, VV Bliskovsky… - Genome biology, 2018 - Springer
Background Lung cancer is the leading cancer diagnosis worldwide and the number one
cause of cancer deaths. Exposure to cigarette smoke, the primary risk factor in lung cancer …