Millions of individuals around the world are afflicted with Parkinson's disease (PD), a
prevalent and incapacitating neurodegenerative disorder. Dr. Reichmann, a distinguished …

Tryptophan (Trp) metabolism involves three primary pathways: the kynurenine (Kyn)
pathway (KP), the 5-hydroxytryptamine (serotonin, 5-HT) pathway, and the indole pathway …

Background Defining the presence of acute and chronic brain inflammation remains a
challenge to clinicians due to the heterogeneity of clinical presentations and aetiologies …

Grapes are rich in phenolic compounds, being important for human health with anti-
inflammatory, antiatherosclerotic, antimutagenic, anticarcinogenic, antibacterial, antiviral …

Introduction Psychological stress can induce affective disorders. Gut microbiota plays a vital
role in emotional function regulation; however, the association between gut microbiota and …

In the era of a steadily increasing lifespan, neurodegenerative diseases among the elderly
present a significant therapeutic and socio-economic challenge. A properly balanced diet …

The present work aimed to identify probiotic candidates from Lithuanian homemade
fermented food samples. A total of 23 lactic acid bacteria were isolated from different …

Obesity is associated with gastrointestinal (GI) tract and central nervous system (CNS)
disorders. High-fat diet (HFD) feeding-induced obesity in mice induces dysbiosis, causing a …

Tryptophan (Trp) is an essential amino acid that can be metabolized via endogenous and
exogenous pathways, including the Kynurenine Pathway, the 5-Hydroxyindole Pathway …

Substance use disorders (SUD) are a serious public health concern globally. Existing
treatment platforms suffer from a lack of effectiveness. The development of immunotherapies …