Cerebral hemorrhage: pathophysiology, treatment, and future directions

J Magid-Bernstein, R Girard, S Polster… - Circulation …, 2022 - ahajournals.org
Intracerebral hemorrhage (ICH) is a devastating form of stroke with high morbidity and
mortality. This review article focuses on the epidemiology, cause, mechanisms of injury …

Angiotensin II signal transduction: an update on mechanisms of physiology and pathophysiology

SJ Forrester, GW Booz, CD Sigmund… - Physiological …, 2018 - journals.physiology.org
The renin-angiotensin-aldosterone system plays crucial roles in cardiovascular physiology
and pathophysiology. However, many of the signaling mechanisms have been unclear. The …

Intracranial aneurysms: pathology, genetics, and molecular mechanisms

Z Xu, YN Rui, JP Hagan, DH Kim - Neuromolecular medicine, 2019 - Springer
Intracranial aneurysms (IA) are local dilatations in cerebral arteries that predominantly affect
the circle of Willis. Occurring in approximately 2–5% of adults, these weakened areas are …

Animal models, pathogenesis, and potential treatment of thoracic aortic aneurysm

Y Wang, IS Panicker, J Anesi, O Sargisson… - International Journal of …, 2024 - mdpi.com
Thoracic aortic aneurysm (TAA) has a prevalence of 0.16–0.34% and an incidence of 7.6
per 100,000 person-years, accounting for 1–2% of all deaths in Western countries …

Disturbed flow's impact on cellular changes indicative of vascular aneurysm initiation, expansion, and rupture: A pathological and methodological review

K Sunderland, J Jiang, F Zhao - Journal of cellular physiology, 2022 - Wiley Online Library
Aneurysms are malformations within the arterial vasculature brought on by the structural
breakdown of the microarchitecture of the vessel wall, with aneurysms posing serious health …

Biology of saccular cerebral aneurysms: a review of current understanding and future directions

VS Fennell, MYS Kalani, G Atwal, NL Martirosyan… - Frontiers in …, 2016 - frontiersin.org
Understanding the biology of intracranial aneurysms is a clinical quandary. How these
aneurysms form, progress, and rupture is poorly understood. Evidence indicates that well …

M1 macrophages are required for murine cerebral aneurysm formation

KW Nowicki, K Hosaka, FJ Walch, EW Scott… - Journal of …, 2018 - jnis.bmj.com
Introduction Macrophages and neutrophils have been separately implicated in cerebral
aneurysm formation. The interactions between different myeloid subsets and the …

Imaging of small animal peripheral artery disease models: recent advancements and translational potential

JB Lin, EH Phillips, TAE Riggins, GS Sangha… - International journal of …, 2015 - mdpi.com
Peripheral artery disease (PAD) is a broad disorder encompassing multiple forms of arterial
disease outside of the heart. As such, PAD development is a multifactorial process with a …

[HTML][HTML] “New Trends in Diabetes, Hypertension, and Cardiovascular Diseases—2nd Edition”

Y Wang, DJ Magliano - International Journal of Molecular Sciences, 2025 - mdpi.com
Cardiovascular diseases (CVDs) encompass a range of conditions affecting both the heart
(eg, coronary heart disease and heart failure [1]) and blood vessels (eg, cerebrovascular …

“New Trends in Diabetes, Hypertension, and Cardiovascular Diseases”

Y Wang, DJ Magliano - International Journal of Molecular Sciences, 2024 - mdpi.com
Cardiovascular disease (CVD) encompasses a range of disorders affecting the heart and
blood vessels, including coronary heart disease and cerebrovascular disease [1] and …