2168 Circulation December 1, 2015 sufficient evidence for health benefit exists to implement
case finding via family history–based screening, cascade screening, or other strategies …

Homozygous familial hypercholesterolemia (HoFH) is an autosomal co-dominant disease
resulting from mutations in both copies of the low-density lipoprotein receptor (LDLR) gene …

Financial declaration A-Economically relevant payments of any kind made to (i) you,(ii) your
spouse/partner or any other person living with you,(iii) any legal person in which any of …

Background: Familial hypercholesterolemia (FH) lead to significant adverse effects in
coronary arteries. Mipomersen is a second-generation antisense oligonucleotide that …

Familial hypercholesterolemia (FH) is a common disorder in which genetic mutations in at
least 1 of several genes lead to significantly increased levels of lipoproteins, in particular …

Background Familial hypercholesterolemia (FH) is a common inherited disorder in which the
severity of atherosclerosis is generally proportional to the extent and duration of elevated …

Familial hypercholesterolemia is an autosomally dominant disorder caused by various
mutations in low-density lipoprotein receptor genes. This will lead to elevated levels of total …

Atualização da Diretriz Brasileira de Hipercolesterolemia Familiar–2021 O relatório abaixo
lista as declarações de interesse conforme relatadas à SBC pelos especialistas durante o …

BACKGROUND: Familial hypercholesterolemia is a treatable genetic condition but remains
underdiagnosed. We reviewed the frequency of pathogenic or likely pathogenic (P/LP) …

Familial hypercholesterolemia (FH) is an autosomal dominant disorder associated with
premature cardiovascular disease (CVD). Mutations in the LDLR, APOB, and PCSK9 genes …