[HTML][HTML] Hyperpolarized 13C MRI: path to clinical translation in oncology

J Kurhanewicz, DB Vigneron, JH Ardenkjaer-Larsen… - Neoplasia, 2019 - Elsevier
This white paper discusses prospects for advancing hyperpolarization technology to better
understand cancer metabolism, identify current obstacles to HP (hyperpolarized) 13 C …

Hyperpolarized 13C MRI: State of the Art and Future Directions

ZJ Wang, MA Ohliger, PEZ Larson, JW Gordon, RA Bok… - Radiology, 2019 - pubs.rsna.org
Hyperpolarized (HP) carbon 13 (13C) MRI is an emerging molecular imaging method that
allows rapid, noninvasive, and pathway-specific investigation of dynamic metabolic and …

Metabolic Imaging of Patients with Prostate Cancer Using Hyperpolarized [1-13C]Pyruvate

SJ Nelson, J Kurhanewicz, DB Vigneron… - Science translational …, 2013 - science.org
This first-in-man imaging study evaluated the safety and feasibility of hyperpolarized [1-13C]
pyruvate as an agent for noninvasively characterizing alterations in tumor metabolism for …

Compressed sensing MRI: a review from signal processing perspective

JC Ye - BMC Biomedical Engineering, 2019 - Springer
Magnetic resonance imaging (MRI) is an inherently slow imaging modality, since it acquires
multi-dimensional k-space data through 1-D free induction decay or echo signals. This often …

NMR hyperpolarization techniques for biomedicine

P Nikolaou, BM Goodson… - Chemistry–A European …, 2015 - Wiley Online Library
Recent developments in NMR hyperpolarization have enabled a wide array of new in vivo
molecular imaging modalities, ranging from functional imaging of the lungs to metabolic …

Accelerated MR spectroscopic imaging—a review of current and emerging techniques

W Bogner, R Otazo, A Henning - NMR in Biomedicine, 2021 - Wiley Online Library
Over more than 30 years in vivo MR spectroscopic imaging (MRSI) has undergone an
enormous evolution from theoretical concepts in the early 1980s to the robust imaging …

Breaking the coherence barrier: A new theory for compressed sensing

B Adcock, AC Hansen, C Poon… - Forum of mathematics …, 2017 - cambridge.org
This paper presents a framework for compressed sensing that bridges a gap between
existing theory and the current use of compressed sensing in many real-world applications …

[HTML][HTML] Deuterium metabolic imaging in the human brain at 9.4 Tesla with high spatial and temporal resolution

L Ruhm, N Avdievich, T Ziegs, AM Nagel… - Neuroimage, 2021 - Elsevier
Purpose To present first highly spatially resolved deuterium metabolic imaging (DMI)
measurements of the human brain acquired with a dedicated coil design and a fast chemical …

Development of methods and feasibility of using hyperpolarized carbon‐13 imaging data for evaluating brain metabolism in patient studies

I Park, PEZ Larson, JW Gordon… - Magnetic resonance …, 2018 - Wiley Online Library
Purpose Hyperpolarized carbon‐13 (13C) metabolic imaging is a noninvasive imaging
modality for evaluating real‐time metabolism. The purpose of this study was to develop and …

MR spectroscopic imaging: principles and recent advances

S Posse, R Otazo, SR Dager… - Journal of Magnetic …, 2013 - Wiley Online Library
MR spectroscopic imaging (MRSI) has become a valuable tool for quantifying metabolic
abnormalities in human brain, prostate, breast and other organs. It is used in routine clinical …