Gut microbiota modulation of chemotherapy efficacy and toxicity
Evidence is growing that the gut microbiota modulates the host response to
chemotherapeutic drugs, with three main clinical outcomes: facilitation of drug efficacy; …
chemotherapeutic drugs, with three main clinical outcomes: facilitation of drug efficacy; …
The gut microbiota influences anticancer immunosurveillance and general health
Discoveries made in the past 5 years indicate that the composition of the intestinal
microbiota has a major influence on the effectiveness of anticancer immunosurveillance and …
microbiota has a major influence on the effectiveness of anticancer immunosurveillance and …
[HTML][HTML] Introduction to host microbiome symbiosis in health and disease
F Malard, J Dore, B Gaugler, M Mohty - Mucosal Immunology, 2021 - Elsevier
Humans share a core intestinal microbiome and yet human microbiome differs by genes,
species, enterotypes (ecology), and gene count (microbial diversity). Achievement of …
species, enterotypes (ecology), and gene count (microbial diversity). Achievement of …
Lactose drives Enterococcus expansion to promote graft-versus-host disease
CK Stein-Thoeringer, KB Nichols, A Lazrak… - Science, 2019 - science.org
Disruption of intestinal microbial communities appears to underlie many human illnesses,
but the mechanisms that promote this dysbiosis and its adverse consequences are poorly …
but the mechanisms that promote this dysbiosis and its adverse consequences are poorly …
Gut microbiome composition predicts infection risk during chemotherapy in children with acute lymphoblastic leukemia
Background Myelosuppression-related infections remain important causes of morbidity and
mortality in children with acute lymphoblastic leukemia (ALL). Methods By analyzing fecal …
mortality in children with acute lymphoblastic leukemia (ALL). Methods By analyzing fecal …
Chemotherapy-induced intestinal microbiota dysbiosis impairs mucosal homeostasis by modulating toll-like receptor signaling pathways
L Wei, XS Wen, CJ **an - International journal of molecular sciences, 2021 - mdpi.com
Chemotherapy-induced intestinal mucositis, a painful debilitating condition affecting up to 40–
100% of patients undergoing chemotherapy, can reduce the patients' quality of life, add …
100% of patients undergoing chemotherapy, can reduce the patients' quality of life, add …
[HTML][HTML] Genomics and emerging biomarkers for immunotherapy of colorectal cancer
JN Kather, N Halama, D Jaeger - Seminars in cancer biology, 2018 - Elsevier
Colorectal cancer (CRC) is a common and lethal disease with a high therapeutic need. For
most patients with metastatic CRC, chemotherapy is the only viable option. Currently …
most patients with metastatic CRC, chemotherapy is the only viable option. Currently …
Gut microbiota diversity after autologous fecal microbiota transfer in acute myeloid leukemia patients
F Malard, A Vekhoff, S Lapusan, F Isnard… - Nature …, 2021 - nature.com
Acute myeloid leukemia (AML) intensive chemotherapy combined with broad-spectrum
antibiotics, leads to gut microbiota dysbiosis promoting pathological conditions and an …
antibiotics, leads to gut microbiota dysbiosis promoting pathological conditions and an …
Febrile neutropenia in acute leukemia. Epidemiology, etiology, pathophysiology and treatment
BA Hansen, Ø Wendelbo, Ø Bruserud… - … of hematology and …, 2019 - pmc.ncbi.nlm.nih.gov
Acute leukemias are a group of aggressive malignant diseases associated with a high
degree of morbidity and mortality. An important cause of both the latter is infectious …
degree of morbidity and mortality. An important cause of both the latter is infectious …
Gut microbiome signatures are predictive of infectious risk following induction therapy for acute myeloid leukemia
Background The majority of studies that provide insights into the influence of the microbiome
on the health of hematologic malignancy patients have concentrated on the transplant …
on the health of hematologic malignancy patients have concentrated on the transplant …