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Persistent inflammatory and non-inflammatory mechanisms in refractory rheumatoid arthritis
Despite nearly three decades of advances in the management of rheumatoid arthritis (RA), a
substantial minority of patients are exposed to multiple DMARDs without necessarily …
substantial minority of patients are exposed to multiple DMARDs without necessarily …
Fatigue in inflammatory rheumatic diseases: current knowledge and areas for future research
Fatigue is a complex phenomenon and an important health concern for many people with
chronic inflammatory rheumatic diseases, such as rheumatoid arthritis, psoriatic arthritis …
chronic inflammatory rheumatic diseases, such as rheumatoid arthritis, psoriatic arthritis …
Synovial fibroblast gene expression is associated with sensory nerve growth and pain in rheumatoid arthritis
It has been presumed that rheumatoid arthritis (RA) joint pain is related to inflammation in
the synovium; however, recent studies reveal that pain scores in patients do not correlate …
the synovium; however, recent studies reveal that pain scores in patients do not correlate …
Society for Immunotherapy of Cancer (SITC) consensus definitions for immune checkpoint inhibitor-associated immune-related adverse events (irAEs) terminology
Immune-related adverse events (irAEs) associated with immune checkpoint inhibitor (ICI)
therapy may vary substantially in their clinical presentation, including natural history …
therapy may vary substantially in their clinical presentation, including natural history …
The many facets of macrophages in rheumatoid arthritis
Macrophages are central to the pathophysiology of rheumatoid arthritis (RA). They constitute
the main source of pro-inflammatory cytokines and chemokines such as TNF and IL-1β, they …
the main source of pro-inflammatory cytokines and chemokines such as TNF and IL-1β, they …
Affective disturbance in rheumatoid arthritis: psychological and disease-related pathways
In addition to recurrent pain, fatigue, and increased rates of physical disability, individuals
with rheumatoid arthritis (RA) have an increased prevalence of some mental health …
with rheumatoid arthritis (RA) have an increased prevalence of some mental health …
Understanding the role of interleukin-6 (IL-6) in the joint and beyond: a comprehensive review of IL-6 inhibition for the management of rheumatoid arthritis
EG Favalli - Rheumatology and therapy, 2020 - Springer
Rheumatoid arthritis (RA) is a chronic, debilitating autoimmune disorder involving
inflammation and progressive destruction of the joints, affecting up to 1% of the population …
inflammation and progressive destruction of the joints, affecting up to 1% of the population …
Measures of fatigue: Bristol rheumatoid arthritis fatigue multi‐dimensional questionnaire (BRAF MDQ), Bristol rheumatoid arthritis fatigue numerical rating scales …
Fatigue is common to all the rheumatic conditions, in varying degrees, and is a frequent,
often severe problem that has major consequences on patients' lives (1–4). In response to …
often severe problem that has major consequences on patients' lives (1–4). In response to …
Fatigue in chronic inflammation-a link to pain pathways
K Louati, F Berenbaum - Arthritis research & therapy, 2015 - Springer
Fatigue is a frequent symptom in several inflammatory diseases, particularly in rheumatic
diseases. Elements of disease activity and cognitive and behavior aspects have been …
diseases. Elements of disease activity and cognitive and behavior aspects have been …
Management of fatigue in rheumatoid arthritis
JE Pope - RMD open, 2020 - rmdopen.bmj.com
Fatigue in rheumatoid arthritis is highly prevalent. It is correlated only weakly with disease
activity but more so with pain, mood, personality features, poor sleep, obesity and …
activity but more so with pain, mood, personality features, poor sleep, obesity and …