Inhibitory potential of nitrogen, oxygen and sulfur containing heterocyclic scaffolds against acetylcholinesterase and butyrylcholinesterase

RJ Obaid, N Naeem, EU Mughal, MM Al-Rooqi… - RSC …, 2022 - pubs.rsc.org
Heterocycles are the key structures in organic chemistry owing to their immense applications
in the biological, chemical, and pharmaceutical fields. Heterocyclic compounds perform …

Latest developments in coumarin-based anticancer agents: mechanism of action and structure–activity relationship studies

M Koley, J Han, VA Soloshonok, S Mojumder… - RSC medicinal …, 2024 - pubs.rsc.org
Many researchers around the world are working on the development of novel anticancer
drugs with different mechanisms of action. In this case, coumarin is a highly promising …

Determination of Antioxidant, Anti-Alzheimer, Antidiabetic, Antiglaucoma and Antimicrobial Effects of Zivzik Pomegranate (Punica granatum)—A Chemical Profiling by …

H Karagecili, E İzol, E Kirecci, İ Gulcin - Life, 2023 - mdpi.com
Zivzik pomegranate (Punica granatum) has recently sparked considerable interest due to its
nutritional and antioxidant properties. To evaluate the antioxidant capacities of P. granatum …

[HTML][HTML] Synthesis and inhibition profiles of N-benzyl-and N-allyl aniline derivatives against carbonic anhydrase and acetylcholinesterase–A molecular docking study

I Mahmudov, Y Demir, Y Sert, Y Abdullayev… - Arabian Journal of …, 2022 - Elsevier
The alkyl and aryl derivatives of aniline are important starting materials in fine organic
synthesis. Allyl bromide and benzyl chloride were taken as substrates for the alkylation …

Comprehensive Metabolite Profiling of Cinnamon (Cinnamomum zeylanicum) Leaf Oil Using LC-HR/MS, GC/MS, and GC-FID: Determination of Antiglaucoma …

M Mutlu, Z Bingol, EM Uc, E Köksal, AC Goren… - Life, 2023 - mdpi.com
In this study, for the first time, the antioxidant and antidiabetic properties of the essential oil
from cinnamon (Cinnamomum zeylanicum) leaves were evaluated and investigated using …

Antioxidant and anticholinergic properties of olivetol

P Taslimi, İ Gulçin - Journal of food biochemistry, 2018 - Wiley Online Library
Olivetol is a pioneer in diverse syntheses of tetrahydrocannabinol. It is produced by a type of
insects, which is used as a pheromone, antiseptic, or repellent agent. In this study, we …

Chalcone and its analogs: Therapeutic and diagnostic applications in Alzheimer's disease

P Thapa, SP Upadhyay, WZ Suo, V Singh, P Gurung… - Bioorganic …, 2021 - Elsevier
Abstract Chalcone [(E)-1, 3-diphenyl-2-propene-1-one], a small molecule with α, β
unsaturated carbonyl group is a precursor or component of many natural flavonoids and …

Anticholinergic, antidiabetic and antioxidant activities of cinnamon (cinnamomum verum) bark extracts: polyphenol contents analysis by LC-MS/MS

I Gulcin, R Kaya, AC Goren, H Akincioglu… - … Journal of Food …, 2019 - Taylor & Francis
Ethanolic (EEC) and aqueous (WEC) extracts of cinnamon (Cinnamomum verum) were
evaluated for their antioxidant profiles by eight distinguished bioanalytical antioxidant …

Chalcone hybrids as potential anticancer agents: Current development, mechanism of action, and structure‐activity relationship

F Gao, G Huang, J **ao - Medicinal research reviews, 2020 - Wiley Online Library
The continuous emergency of drug‐resistant cancers and the low specificity of anticancer
agents have been the major challenges in the control and treatment of cancer, making an …

Insights of 8-hydroxyquinolines: A novel target in medicinal chemistry

R Gupta, V Luxami, K Paul - Bioorganic chemistry, 2021 - Elsevier
Hydroxyquinoline (8-HQ) is a significant heterocyclic scaffold in organic and analytical
chemistry because of the properties of chromophore and is used to detect various metal ions …