Impaired mitochondrial function in psychiatric disorders

H Manji, T Kato, NA Di Prospero, S Ness… - Nature reviews …, 2012 - nature.com
Major psychiatric illnesses such as mood disorders and schizophrenia are chronic, recurrent
mental illnesses that affect the lives of millions of individuals. Although these disorders have …

Use of Y chromosome and mitochondrial DNA population structure in tracing human migrations

PA Underhill, T Kivisild - Annu. Rev. Genet., 2007 - annualreviews.org
Well-resolved molecular gene trees illustrate the concept of descent with modification and
exhibit the opposing processes of drift and migration, both of which influence population …

Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation

M Van Oven, M Kayser - Human mutation, 2009 - Wiley Online Library
Human mitochondrial DNA is widely used as tool in many fields including evolutionary
anthropology and population history, medical genetics, genetic genealogy, and forensic …

DNA analysis of an early modern human from Tianyuan Cave, China

Q Fu, M Meyer, X Gao, U Stenzel… - Proceedings of the …, 2013 - National Acad Sciences
Hominins with morphology similar to present-day humans appear in the fossil record across
Eurasia between 40,000 and 50,000 y ago. The genetic relationships between these early …

Correcting for purifying selection: an improved human mitochondrial molecular clock

P Soares, L Ermini, N Thomson, M Mormina… - The American Journal of …, 2009 - cell.com
There is currently no calibration available for the whole human mtDNA genome,
incorporating both coding and control regions. Furthermore, as several authors have pointed …

The phylogeny of the four pan-American MtDNA haplogroups: implications for evolutionary and disease studies

A Achilli, UA Perego, CM Bravi, MD Coble, QP Kong… - PLoS …, 2008 - journals.plos.org
Only a limited number of complete mitochondrial genome sequences belonging to Native
American haplogroups were available until recently, which left America as the continent with …

The first Korean genome sequence and analysis: full genome sequencing for a socio-ethnic group

SM Ahn, TH Kim, S Lee, D Kim, H Ghang… - Genome …, 2009 - genome.cshlp.org
We present the first Korean individual genome sequence (SJK) and analysis results. The
diploid genome of a Korean male was sequenced to 28.95-fold redundancy using the …

Phylogeographic analysis of mitochondrial DNA in northern Asian populations

M Derenko, B Malyarchuk, T Grzybowski… - The American Journal of …, 2007 - cell.com
To elucidate the human colonization process of northern Asia and human dispersals to the
Americas, a diverse subset of 71 mitochondrial DNA (mtDNA) lineages was chosen for …

Genetic evidence of paleolithic colonization and neolithic expansion of modern humans on the tibetan plateau

X Qi, C Cui, Y Peng, X Zhang, Z Yang… - Molecular biology …, 2013 - academic.oup.com
Tibetans live on the highest plateau in the world, their current population size is
approximately 5 million, and most of them live at an altitude exceeding 3,500 m. Therefore …

Mitochondrial genome evidence reveals successful Late Paleolithic settlement on the Tibetan Plateau

M Zhao, QP Kong, HW Wang… - Proceedings of the …, 2009 - National Acad Sciences
Due to its numerous environmental extremes, the Tibetan Plateau—the world's highest
plateau—is one of the most challenging areas of modern human settlement. Archaeological …