This article reviews recent empirical literature on the prevalence, correlates, assessment,
and treatment of preschool-onset internalizing disorders. Major advances in the acceptance …

A swiftly growing volume of literature, comprising both human and animal studies and
employing both observational and experimental designs, has documented striking individual …

Background Meta-analyses have yielded contradictory findings concerning the role of 5-
HTTLPR in interaction with stress (GxE) in depression. The current meta-analysis …

This paper argues that there is a revolution afoot in the developmental science of gene–
environment interplay. We summarize, for an audience of developmental researchers and …

The burgeoning field of gene-by-environment (G× E) interactions has revealed fascinating
biological insights, particularly in the realm of stress-, anxiety-, and depression-related …

Objectives Differences in DNA methylation have been associated with early life adversity,
suggesting that alterations in methylation function as one pathway through which adverse …

Anxiety disorders that are the most commonly occurring psychiatric disorders in childhood,
are associated with a range of social and educational impairments and often continue into …

Psychopathology is a process: it unfolds over time and involves several different factors. To
extend our knowledge of such process, it is vital to understand the trajectories that lead to …

Two sets of evidence reviewed herein, one indicating that prenatal stress is associated with
elevated behavioral and physiological dysregulation and the other that such phenotypic …

Background A growing body of research now supports the validity, clinical significance, and
long-term negative impact of depression occurring during the preschool period. However …