Recent progress of SELEX methods for screening nucleic acid aptamers
C Zhu, Z Feng, H Qin, L Chen, M Yan, L Li, F Qu - Talanta, 2024 - Elsevier
Nucleic acid aptamers are oligonucleotide sequences screened by an in vitro methodology
called Systematic Evolution of Ligands by Exponential Enrichment (SELEX). Known as …
called Systematic Evolution of Ligands by Exponential Enrichment (SELEX). Known as …
Aptamer-based biosensors for virus protein detection
B Lou, Y Liu, M Shi, J Chen, K Li, Y Tan, L Chen… - TrAC Trends in …, 2022 - Elsevier
Virus threatens life health seriously. The accurate early diagnosis of the virus is vital for
clinical control and treatment of virus infection. Aptamers are small single-stranded …
clinical control and treatment of virus infection. Aptamers are small single-stranded …
Development of Nucleic‐Acid‐Based Electrochemical Biosensors for Clinical Applications
Nucleic acids are remarkable molecules. In addition to Watson–Crick base pairing, the
different structural motifs of these molecules can bind non‐nucleic acid targets or catalyze …
different structural motifs of these molecules can bind non‐nucleic acid targets or catalyze …
Translation of aptamers toward clinical diagnosis and commercialization
S Liu, Y Xu, X Jiang, H Tan, B Ying - Biosensors and Bioelectronics, 2022 - Elsevier
The dominance of antibodies in diagnostics has gradually changed following the discovery
of aptamers in the early 1990s. Aptamers offer inherent advantages over traditional …
of aptamers in the early 1990s. Aptamers offer inherent advantages over traditional …
Computational tools for aptamer identification and optimization
D Sun, M Sun, J Zhang, X Lin, Y Zhang, F Lin… - TrAC Trends in …, 2022 - Elsevier
Aptamers are single-stranded DNA or RNA oligonucleotides that can selectively bind to a
specific target. They are generally obtained by SELEX, but the procedure is challenging and …
specific target. They are generally obtained by SELEX, but the procedure is challenging and …
Diagnostics and analysis of SARS-CoV-2: current status, recent advances, challenges and perspectives
T Dong, M Wang, J Liu, P Ma, S Pang, W Liu… - Chemical Science, 2023 - pubs.rsc.org
The disastrous spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
has induced severe public healthcare issues and weakened the global economy …
has induced severe public healthcare issues and weakened the global economy …
A universal DNA aptamer that recognizes spike proteins of diverse SARS‐CoV‐2 variants of concern
We report on a unique DNA aptamer, denoted MSA52, that displays universally high affinity
for the spike proteins of wildtype SARS‐CoV‐2 as well as the Alpha, Beta, Gamma, Epsilon …
for the spike proteins of wildtype SARS‐CoV‐2 as well as the Alpha, Beta, Gamma, Epsilon …
Electrochemical aptasensing of SARS-CoV-2 based on triangular prism DNA nanostructures and dumbbell hybridization chain reaction
Y Jiang, X Chen, N Feng, P Miao - Analytical Chemistry, 2022 - ACS Publications
Development of convenient, accurate, and sensitive methods for rapid screening of severe
acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) infection is highly desired. In this …
acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) infection is highly desired. In this …
Design and prediction of aptamers assisted by in silico methods
SJ Lee, J Cho, BH Lee, D Hwang, JW Park - Biomedicines, 2023 - mdpi.com
An aptamer is a single-stranded DNA or RNA that binds to a specific target with high binding
affinity. Aptamers are developed through the process of systematic evolution of ligands by …
affinity. Aptamers are developed through the process of systematic evolution of ligands by …
Aptamer sandwich assay for the detection of SARS-CoV-2 spike protein antigen
M Svobodova, V Skouridou, M Jauset-Rubio… - ACS …, 2021 - ACS Publications
The novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) emerged at the
end of 2019, resulting in the ongoing COVID-19 pandemic. The high transmissibility of the …
end of 2019, resulting in the ongoing COVID-19 pandemic. The high transmissibility of the …