Alzheimer's disease (AD) is an age‐associated neurodegenerative disorder with
multifactorial etiology, intersecting genetic and environmental risk factors, and a lack of …

Statins are a family of drugs that are used for treating hyperlipidaemia with a recognized
capacity to prevent cardiovascular disease events. They inhibit β‐hydroxy β‐methylglutaryl …

Every 5 years, the JAS publishes guidelines for the treatment of dyslipidemia and
atherosclerosis. To date, this society has released four such guidelines. Since 2007, the JAS …

Background Findings from clinical trials of proprotein convertase subtilisin–kexin type 9
(PCSK9) inhibitors have led to concern that these drugs or the low levels of low-density …

Hydroxy-methyl-glutaryl-coenzyme A (HMG-CoA) reductase inhibitors or statins are well
tolerated, but associated with various statin-associated symptoms (SAS), including statin …

Presenilin mutations that alter γ-secretase activity cause familial Alzheimer's disease (AD),
whereas ApoE4, an apolipoprotein for cholesterol transport, predisposes to sporadic AD …

Background Reducing high blood cholesterol, a risk factor for cardiovascular disease (CVD)
events in people with and without a past history of coronary heart disease (CHD) is an …

Alzheimer's disease (AD) is the most common form of dementia and it is characterized by the
deposition of amyloid-β (Aβ) plaques and neurofibrillary tangles in the brain. However, the …

Alzheimer's disease (AD) was used to describe pre-senile dementia to differentiate it from
senile dementia, which develops in the adult age group of more than 65 years. AD is …

Importance The etiologic factors of late-life depression are still poorly understood. Recent
evidence suggests that microvascular dysfunction is associated with depression, which may …