Circulating tumor cells: biology and clinical significance

D Lin, L Shen, M Luo, K Zhang, J Li, Q Yang… - Signal transduction and …, 2021 - nature.com
Circulating tumor cells (CTCs) are tumor cells that have sloughed off the primary tumor and
extravasate into and circulate in the blood. Understanding of the metastatic cascade of CTCs …

Circulating tumour cells for early detection of clinically relevant cancer

R Lawrence, M Watters, CR Davies, K Pantel… - Nature Reviews Clinical …, 2023 - nature.com
Given that cancer mortality is usually a result of late diagnosis, efforts in the field of early
detection are paramount to reducing cancer-related deaths and improving patient outcomes …

Circulating tumor cell detection technologies and clinical utility: Challenges and opportunities

Z Habli, W AlChamaa, R Saab, H Kadara, ML Khraiche - Cancers, 2020 - mdpi.com
The potential clinical utility of circulating tumor cells (CTCs) in the diagnosis and
management of cancer has drawn a lot of attention in the past 10 years. CTCs disseminate …

Technologies for circulating tumor cell separation from whole blood

P Bankó, SY Lee, V Nagygyörgy, M Zrínyi… - Journal of hematology & …, 2019 - Springer
The importance of early cancer diagnosis and improved cancer therapy has been clear for
years and has initiated worldwide research towards new possibilities in the care strategy of …

Lateral flow assays towards point-of-care cancer detection: A review of current progress and future trends

T Mahmoudi, M de la Guardia, B Baradaran - TrAC Trends in Analytical …, 2020 - Elsevier
Cancer is one of the main causes of mortality and morbidity worldwide. However, its early
non-invasive detection via quantification of appropriate biomarkers can significantly reduce …

Microfluidic-based technologies for CTC isolation: a review of 10 years of intense efforts towards liquid biopsy

L Descamps, D Le Roy, AL Deman - International Journal of Molecular …, 2022 - mdpi.com
The selection of circulating tumor cells (CTCs) directly from blood as a real-time liquid
biopsy has received increasing attention over the past ten years, and further analysis of …

Integrative serum metabolic fingerprints based multi‐modal platforms for lung adenocarcinoma early detection and pulmonary nodule classification

L Wang, M Zhang, X Pan, M Zhao, L Huang… - Advanced …, 2022 - Wiley Online Library
Identification of novel non‐invasive biomarkers is critical for the early diagnosis of lung
adenocarcinoma (LUAD), especially for the accurate classification of pulmonary nodule …

Platelet–leukocyte hybrid membrane‐coated immunomagnetic beads for highly efficient and highly specific isolation of circulating tumor cells

L Rao, QF Meng, Q Huang, Z Wang… - Advanced Functional …, 2018 - Wiley Online Library
Biomimetic cell‐membrane‐camouflaged nanoparticles with desirable features have been
widely used for various biomedical applications. However, the current research focuses on …

Metal-mediated Fe3O4@ polydopamine-aptamer capture nanoprobe coupling multifunctional MXene@ Au@ Pt nanozyme for direct and portable photothermal …

L Yang, H Guo, T Hou, J Zhang, F Li - Biosensors and Bioelectronics, 2023 - Elsevier
Breast cancer (BC) is the most common cancer in the world and circulating tumor cells
(CTCs) are reliable biomarkers for early breast cancer diagnosis in a non-invasive manner …

Updates on liquid biopsy: Current trends and future perspectives for clinical application in solid tumors

P Pinzani, V D'Argenio, M Del Re… - Clinical Chemistry and …, 2021 - degruyter.com
Despite advances in screening and therapeutics cancer continues to be one of the major
causes of morbidity and mortality worldwide. The molecular profile of tumor is routinely …