Macrophage-targeted nanomedicine for the diagnosis and treatment of atherosclerosis
Nanotechnology could improve our understanding of the pathophysiology of atherosclerosis
and contribute to the development of novel diagnostic and therapeutic strategies to further …
and contribute to the development of novel diagnostic and therapeutic strategies to further …
Nanogels: Synthesis, properties, and recent biomedical applications
Nanogels, also termed hydrogel nanoparticles, have the properties and functions of both
nanomaterials and hydrogels. Till date, a considerable number of nanogels have been …
nanomaterials and hydrogels. Till date, a considerable number of nanogels have been …
Applications of nanoparticles in biomedical imaging
An urgent need for early detection and diagnosis of diseases continuously pushes the
advancements of imaging modalities and contrast agents. Current challenges remain for fast …
advancements of imaging modalities and contrast agents. Current challenges remain for fast …
Brief update on endocytosis of nanomedicines
The complexity of nanoscale interactions between biomaterials and cells has limited the
realization of the ultimate vision of nanotechnology in diagnostics and therapeutics. As such …
realization of the ultimate vision of nanotechnology in diagnostics and therapeutics. As such …
Dysfunctional HDL and atherosclerotic cardiovascular disease
RS Rosenson, HB Brewer Jr, BJ Ansell… - Nature reviews …, 2016 - nature.com
High-density lipoproteins (HDLs) protect against atherosclerosis by removing excess
cholesterol from macrophages through the ATP-binding cassette transporter A1 (ABCA1) …
cholesterol from macrophages through the ATP-binding cassette transporter A1 (ABCA1) …
Recommendation on design, execution, and reporting of animal atherosclerosis studies: a scientific statement from the American Heart Association
Animal studies are a foundation for defining mechanisms of atherosclerosis and potential
targets of drugs to prevent lesion development or reverse the disease. In the current …
targets of drugs to prevent lesion development or reverse the disease. In the current …
Berberine treats atherosclerosis via a vitamine-like effect down-regulating Choline-TMA-TMAO production pathway in gut microbiota
SR Ma, Q Tong, Y Lin, LB Pan, J Fu, R Peng… - Signal transduction and …, 2022 - nature.com
Abstract Trimethylamine-N-oxide (TMAO) derived from the gut microbiota is an atherogenic
metabolite. This study investigates whether or not berberine (BBR) could reduce TMAO …
metabolite. This study investigates whether or not berberine (BBR) could reduce TMAO …
Polymeric nanostructures for imaging and therapy
Medical diagnosis and therapy are essential for providing patients with proper care,
although inefficient diagnosis and therapy are usually associated with either improper …
although inefficient diagnosis and therapy are usually associated with either improper …
Recent advances and future prospects of iron oxide nanoparticles in biomedicine and diagnostics
Superparamagnetic iron oxide nanoparticles (SPIONs) are considered as chemically inert
materials and, therefore, being extensively applied in the areas of imaging, targeting, drug …
materials and, therefore, being extensively applied in the areas of imaging, targeting, drug …
Anti-atherosclerotic therapies: milestones, challenges, and emerging innovations
I Hetherington, H Totary-Jain - Molecular Therapy, 2022 - cell.com
Atherosclerosis is the main underlying pathology for many cardiovascular diseases (CVDs),
which are the leading cause of death globally and represent a serious health crisis …
which are the leading cause of death globally and represent a serious health crisis …