Virology, epidemiology, pathogenesis, and control of enterovirus 71
First isolated in California, USA, in 1969, enterovirus 71 (EV71) is a major public health
issue across the Asia-Pacific region and beyond. The virus, which is closely related to …
issue across the Asia-Pacific region and beyond. The virus, which is closely related to …
[HTML][HTML] Vero cell upstream bioprocess development for the production of viral vectors and vaccines
The Vero cell line is considered the most used continuous cell line for the production of viral
vectors and vaccines. Historically, it is the first cell line that was approved by the WHO for the …
vectors and vaccines. Historically, it is the first cell line that was approved by the WHO for the …
Development of suspension adapted Vero cell culture process technology for production of viral vaccines
CF Shen, C Guilbault, X Li, SM Elahi, S Ansorge… - Vaccine, 2019 - Elsevier
Vero cells are considered as the most widely accepted continuous cell line by the regulatory
authorities (such as WHO) for the manufacture of viral vaccines for human use. The growth …
authorities (such as WHO) for the manufacture of viral vaccines for human use. The growth …
EV71: an emerging infectious disease vaccine target in the Far East?
J Xu, Y Qian, S Wang, JMG Serrano, W Li, Z Huang… - Vaccine, 2010 - Elsevier
Hand, foot, and mouth disease (HFMD) is a common viral illness in infants and children
caused by viruses that belong to the enterovirus genus of the picornavirus family. Although …
caused by viruses that belong to the enterovirus genus of the picornavirus family. Although …
Assessment of immunogenic potential of Vero adapted formalin inactivated vaccine derived from novel ECSA genotype of Chikungunya virus
The recent resurgence of Chikungunya virus (CHIKV) in India and Indian Ocean Islands with
unusual clinical severity is a matter of great public health concern. Despite the fact that …
unusual clinical severity is a matter of great public health concern. Despite the fact that …
Purification and characterization of enterovirus 71 viral particles produced from vero cells grown in a serum-free microcarrier bioreactor system
CC Liu, MS Guo, FHY Lin, KN Hsiao, KHW Chang… - PloS one, 2011 - journals.plos.org
Background Enterovirus 71 (EV71) infections manifest most commonly as a childhood
exanthema known as hand-foot-and-mouth disease (HFMD) and can cause neurological …
exanthema known as hand-foot-and-mouth disease (HFMD) and can cause neurological …
Cooperative effect of the attenuation determinants derived from poliovirus sabin 1 strain is essential for attenuation of enterovirus 71 in the NOD/SCID mouse infection …
M Arita, Y Ami, T Wakita, H Shimizu - Journal of virology, 2008 - Am Soc Microbiol
ABSTRACT Enterovirus 71 (EV71) is a causative agent of hand, foot, and mouth disease
and is also associated with serious neurological disorders. An attenuated EV71 strain [EV71 …
and is also associated with serious neurological disorders. An attenuated EV71 strain [EV71 …
Formalin-inactivated EV71 vaccine candidate induced cross-neutralizing antibody against subgenotypes B1, B4, B5 and C4A in adult volunteers
AH Chou, CC Liu, JY Chang, R Jiang, YC Hsieh… - PLoS …, 2013 - journals.plos.org
Background Enterovirus 71 (EV71) has caused several epidemics of hand, foot and mouth
diseases (HFMD) in Asia. No effective EV71 vaccine is available. A randomized and open …
diseases (HFMD) in Asia. No effective EV71 vaccine is available. A randomized and open …
Characterization of pharmacologically active compounds that inhibit poliovirus and enterovirus 71 infectivity
M Arita, T Wakita, H Shimizu - Journal of General Virology, 2008 - microbiologyresearch.org
Poliovirus (PV) and enterovirus 71 (EV71) cause severe neurological symptoms in their
infections of the central nervous system. To identify compounds with anti-PV and anti-EV71 …
infections of the central nervous system. To identify compounds with anti-PV and anti-EV71 …
Human SCARB2 transgenic mice as an infectious animal model for enterovirus 71
YW Lin, SL Yu, HY Shao, HY Lin, CC Liu, KN Hsiao… - PloS one, 2013 - journals.plos.org
Enterovirus 71 (EV71) and coxsackievirus (CVA) are the most common causative factors for
hand, foot, and mouth disease (HFMD) and neurological disorders in children. Lack of a …
hand, foot, and mouth disease (HFMD) and neurological disorders in children. Lack of a …